| 8-9 ' linked neolignans with cytotoxicity from Alpinia conchigera | |
| Xu, Jun-Ju1,2; Zeng, Guang-Zhi3; Yang, Sheng-Chao1; Shen, Yong1; Tan, Ning-Hua3 | |
| 通讯作者 | Shen,Y (reprint author),Yunnan Agr Univ,Yunnan Res Ctr Good Agr Practice Dominant Chinese,Kunming 650201,Peoples R China.,pharmsy@sina.com ; nhtan@mail.kib.ac.cn |
| 2013-12-01 | |
| 发表期刊 | FITOTERAPIA
 |
| ISSN | 0367-326X |
| 卷号 | 91页码:82-86 |
| 摘要 | Five new 8-9' linked neolignans conchigeranals A-E (1-5), together with three known compounds galanganal (6), galanganols A (7) and B (8), were isolated from the whole plant of Alpinia conchigera. Their structures were established by spectroscopic analysis, including 2D-NMR spectroscopic techniques. Cytotoxicities of compounds 1-8 were tested against two cancer cell lines A549 and Hela. Results showed that 4, 5, 7 and 8 exhibited cytotoxicity against A549 with the IC50 values of 1236, 9.72, 10.26, 13.05 mu g/ml, respectively, and 1-8 against Hela with the IC50 values from 1.53 to 5.29 mu g/ml. (C) 2013 Published by Elsevier B.V. |
| 关键词 | Zingiberaceae Alpinia Conchigera Neolignans Conchigeranals A-e Cytotoxicity |
| 学科领域 | Pharmacology & Pharmacy |
| DOI | 10.1016/j.fitote.2013.08.011 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000327574300012 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/17413 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Yunnan Agr Univ, Yunnan Res Ctr Good Agr Practice Dominant Chinese, Kunming 650201, Peoples R China 2.Yunnan Agr Univ, Coll Tobacco Sci, Kunming 650201, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Jun-Ju,Zeng, Guang-Zhi,Yang, Sheng-Chao,et al. 8-9 ' linked neolignans with cytotoxicity from Alpinia conchigera[J]. FITOTERAPIA,2013,91:82-86. |
| APA | Xu, Jun-Ju,Zeng, Guang-Zhi,Yang, Sheng-Chao,Shen, Yong,&Tan, Ning-Hua.(2013).8-9 ' linked neolignans with cytotoxicity from Alpinia conchigera.FITOTERAPIA,91,82-86. |
| MLA | Xu, Jun-Ju,et al."8-9 ' linked neolignans with cytotoxicity from Alpinia conchigera".FITOTERAPIA 91(2013):82-86. |
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| Xu-2013-8-9 ' linked（326KB） | 开放获取 | CC BY-NC-SA | 浏览 下载 | |||
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