8-9 ' linked neolignans with cytotoxicity from Alpinia conchigera
Xu, Jun-Ju1,2; Zeng, Guang-Zhi3; Yang, Sheng-Chao1; Shen, Yong1; Tan, Ning-Hua3
2013-12-01
发表期刊FITOTERAPIA
ISSN0367-326X
卷号91页码:82-86
摘要Five new 8-9' linked neolignans conchigeranals A-E (1-5), together with three known compounds galanganal (6), galanganols A (7) and B (8), were isolated from the whole plant of Alpinia conchigera. Their structures were established by spectroscopic analysis, including 2D-NMR spectroscopic techniques. Cytotoxicities of compounds 1-8 were tested against two cancer cell lines A549 and Hela. Results showed that 4, 5, 7 and 8 exhibited cytotoxicity against A549 with the IC50 values of 1236, 9.72, 10.26, 13.05 mu g/ml, respectively, and 1-8 against Hela with the IC50 values from 1.53 to 5.29 mu g/ml. (C) 2013 Published by Elsevier B.V.
关键词Zingiberaceae Alpinia Conchigera Neolignans Conchigeranals A-e Cytotoxicity
资助信息National Natural Science Foundation of China [31000159, 31360080]; National Natural Science Foundation of China(31000159; 31360080)
收录类别SCI
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/17413
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Yunnan Agr Univ, Yunnan Res Ctr Good Agr Practice Dominant Chinese, Kunming 650201, Peoples R China
2.Yunnan Agr Univ, Coll Tobacco Sci, Kunming 650201, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
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Xu, Jun-Ju,Zeng, Guang-Zhi,Yang, Sheng-Chao,et al. 8-9 ' linked neolignans with cytotoxicity from Alpinia conchigera[J]. FITOTERAPIA,2013,91:82-86.
APA Xu, Jun-Ju,Zeng, Guang-Zhi,Yang, Sheng-Chao,Shen, Yong,&Tan, Ning-Hua.(2013).8-9 ' linked neolignans with cytotoxicity from Alpinia conchigera.FITOTERAPIA,91,82-86.
MLA Xu, Jun-Ju,et al."8-9 ' linked neolignans with cytotoxicity from Alpinia conchigera".FITOTERAPIA 91(2013):82-86.
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