Two New Triterpenoids from Gelsemium elegans and Aglaia odorata
Liu, Bing1,2,6; Yang, Lin2; Xu, You-Kai1,2; Liao, Shang-Gao3,4; Luo, Huai-Rong5; Na, Zhi2
2013-10-01
发表期刊NATURAL PRODUCT COMMUNICATIONS
ISSN1934-578X
卷号8期号:10页码:1373-1376
摘要Eleganoside A (1) and odoratanone A (15), a triterpenoid trisaccharide glycoside and a nortriterpenoid, together with twelve known compounds (2-13) and a mixture of cerebrosides (14) were isolated from Gelsemium elegans and Aglaia odorata. Their structures were elucidated by extensive spectroscopic and spectrometric analysis. Eleganoside A (1) features a 3-O-alpha-L-rhamnopyranosyl (1 -> 4)-beta-D-glucopyranosyl (1 -> 4)-beta-D-glucopyranoside of a peculiar 3,16-dihydroxyl-lanosta-8,24-dien-26-oic acid triterpenoid skeleton, and odoratanone A (15) is a 29-norcycloartane-type triterpenoid bearing an unusual five-membered methyl acetal ring. Anti-acetylcholinesterase/butyrylcholinesterase (AChE/BChE) assay indicated that at 50 mu M, ethyl caffeate (5) was promising as a dual inhibitor of AChE and BChE, and paeonol (3) and 24-hydroperoxy-24-vinylcholesterol (9) exhibited BChE-selective inhibition.
关键词Gelsemium Elegans Aglaia Odorata Eleganoside a Odoratanone a Ache/bche
资助信息Chinese Academy of Sciences [KSCX2-YW-R-172];Ethnobotanical Investigation of Plants for Industrialization in Southwest China [SQ2012FY4910027]
学科领域Pharmacology & Pharmacy ; Food Science & Technology
收录类别SCI
语种英语
WOS研究方向Pharmacology & Pharmacy ; Food Science & Technology
WOS类目Chemistry, Medicinal ; Food Science & Technology
WOS记录号WOS:000326127900008
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/17404
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Key Lab Trop Forest Ecol, Xishuangbanna Trop Bot Garden, Mengla 666303, Yunnan, Peoples R China
2.Chinese Acad Sci, Key Lab Trop Plant Resource Sci, Xishuangbanna Trop Bot Garden, Mengla 666303, Yunnan, Peoples R China
3.Guiyang Med Coll, Engn Res Ctr Dev & Applicat Ethn Med, Sch Pharm, Guiyang 550004, Guizhuo, Peoples R China
4.Guiyang Med Coll, TCM, Sch Pharm, Guiyang 550004, Guizhuo, Peoples R China
5.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
6.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
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Liu, Bing,Yang, Lin,Xu, You-Kai,et al. Two New Triterpenoids from Gelsemium elegans and Aglaia odorata[J]. NATURAL PRODUCT COMMUNICATIONS,2013,8(10):1373-1376.
APA Liu, Bing,Yang, Lin,Xu, You-Kai,Liao, Shang-Gao,Luo, Huai-Rong,&Na, Zhi.(2013).Two New Triterpenoids from Gelsemium elegans and Aglaia odorata.NATURAL PRODUCT COMMUNICATIONS,8(10),1373-1376.
MLA Liu, Bing,et al."Two New Triterpenoids from Gelsemium elegans and Aglaia odorata".NATURAL PRODUCT COMMUNICATIONS 8.10(2013):1373-1376.
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