Diterpenoid compounds from Vitex agnus-castus

	Diterpenoid compounds from Vitex agnus-castus
	Pal, Mahesh 1,2; Li, Sheng-Hong2 ; Tewari, Shri Krishan 1; Sun, Han-Dong2
通讯作者	Pal, M (reprint author), Natl Bot Res Inst, CSIR, Phytochem Div, Lucknow 226001, Uttar Pradesh, India.,drmpal.nbri@rediffmail.com
	2013-09-01
发表期刊	CHEMISTRY OF NATURAL COMPOUNDS
ISSN	0009-3130
卷号	49 期号:4 页码:635-638
摘要	A new diterpenoid alkaloid having an alpha,beta-unsaturated gamma-lactam moiety, 9 alpha-hydroxy-13(14)-labden-16,15-amide (1), together with five known ones, was isolated from the fruits of Vitex angus-castus. The structure of 1 was elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques.The cytotoxicity of each compound was evaluated against human chronic myelogenous leukemia (K562) cell lines. Compound 1 was found to be the most potent with IC50 value of 0.70 mu g/mL.
关键词	Diterpenoid Vitex Agnus-castus Verbenaceae Vitexlactam Cytotoxicity
学科领域	Chemistry, Medicinal ; Chemistry, Organic
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000324830200012
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/17284
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Natl Bot Res Inst, CSIR, Phytochem Div, Lucknow 226001, Uttar Pradesh, India 2.Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Pal, Mahesh,Li, Sheng-Hong,Tewari, Shri Krishan,et al. Diterpenoid compounds from Vitex agnus-castus[J]. CHEMISTRY OF NATURAL COMPOUNDS,2013,49(4):635-638.
APA	Pal, Mahesh,Li, Sheng-Hong,Tewari, Shri Krishan,&Sun, Han-Dong.(2013).Diterpenoid compounds from Vitex agnus-castus.CHEMISTRY OF NATURAL COMPOUNDS,49(4),635-638.
MLA	Pal, Mahesh,et al."Diterpenoid compounds from Vitex agnus-castus".CHEMISTRY OF NATURAL COMPOUNDS 49.4(2013):635-638.

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