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题名: Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope
作者: Lian, Wu1, 2; Wu, Mingyi1; Huang, Ning3, 4; Gao, Na1; Xiao, Chuang1, 2; Li, Zi1; Zhang, Zhigang1; Zheng, Yongtang3, 4; Peng, Wenlie2; null(赵金华)1
刊名: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
关键词: Glycosaminoglycan ; Anti-human immunodeficiency virus activity ; Envelope glycoprotein 120 ; Cluster of Differentiation 4 induced epitope ; Biolayer interferometry ; Structure-activity relationship
英文摘要: Background: Fucosylated glycosaminoglycan (FG) is a novel glycosaminoglycan with a chondroitin sulfate-like backbone and fucose sulfate branches. The aim of this study is to investigate the mechanism and structure-activity relationships (SAR) of FG for combating HIV-1 infection.
出版日期: 2013-10-01
卷号: 1830, 期号:10, 页码:4681-4691
语种: 英语
收录类别: SCI
学科分类: Biochemistry & Molecular Biology ; Biophysics
ISSN号: 0304-4165
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/17281
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Sun Yat Sen Univ, Sch Life Sci, Guangzhou 510275, Guangdong, Peoples R China
3.Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Yunnan, Peoples R China
4.Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China

Recommended Citation:
Lian, Wu;Wu, Mingyi;Huang, Ning;Gao, Na;Xiao, Chuang;Li, Zi;Zhang, Zhigang;Zheng, Yongtang;Peng, Wenlie;Zhao, Jinhua.Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope,BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,2013,1830(10):4681-4691
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