Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope
Lian, Wu1,2; Wu, Mingyi1; Huang, Ning3,4; Gao, Na1; Xiao, Chuang1,2; Li, Zi1; Zhang, Zhigang1; Zheng, Yongtang3,4; Peng, Wenlie2; Zhao, Jinhua1
2013-10-01
发表期刊BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
ISSN0304-4165
卷号1830期号:10页码:4681-4691
摘要Background: Fucosylated glycosaminoglycan (FG) is a novel glycosaminoglycan with a chondroitin sulfate-like backbone and fucose sulfate branches. The aim of this study is to investigate the mechanism and structure-activity relationships (SAR) of FG for combating HIV-1 infection.
关键词Glycosaminoglycan Anti-human Immunodeficiency Virus Activity Envelope Glycoprotein 120 Cluster Of Differentiation 4 Induced Epitope Biolayer Interferometry Structure-activity Relationship
资助信息Yunnan Provincial Science and Technology Department in China [2010CI116, 2012BC011, 2012FB177]; National Natural Science Foundation of China [81102372]; Outstanding Technical Talent Foundation of the Chinese Academy of Sciences; West Light Foundation of the Chinese Academy of Sciences
学科领域Biochemistry & Molecular Biology ; Biophysics
DOI10.1016/j.bbagen.2013.06.003
收录类别SCI
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Biophysics
WOS类目Biochemistry & Molecular Biology ; Biophysics
WOS记录号WOS:000323854900031
引用统计
被引频次:24[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/17281
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Sun Yat Sen Univ, Sch Life Sci, Guangzhou 510275, Guangdong, Peoples R China
3.Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Yunnan, Peoples R China
4.Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China
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Lian, Wu,Wu, Mingyi,Huang, Ning,et al. Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope[J]. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,2013,1830(10):4681-4691.
APA Lian, Wu.,Wu, Mingyi.,Huang, Ning.,Gao, Na.,Xiao, Chuang.,...&Zhao, Jinhua.(2013).Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,1830(10),4681-4691.
MLA Lian, Wu,et al."Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope".BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1830.10(2013):4681-4691.
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