A new cytotoxic homoisoflavonoid from Dracaena cambodiana
Liu, Jian1; Mei, Wen-Li1; Wu, Jiao1; Zhao, You-Xing2; Peng, Ming1; Dai, Hao-Fu1
2009
Source PublicationJOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume11Issue:2Pages:192-195
AbstractA new homoisoflavonoid, named cambodianol (1), together with the two known flavanes, (2S)-7,3'-dihydroxy-4'-methoxy-8-methylflavane (2) and (2R)-7,4'-dihydroxy-8-methylflavane (3), were isolated from the stems of Dracaena cambodiana. Their structures were determined based on HR-ESI-MS and spectroscopic techniques (UV, IR, 1D-, and 2D-NMR). Compound 1 exhibited significant cytotoxic activities against K562 and SGC-7901 with the IC50 values of 1.4 and 2.9g/ml, respectively.
KeywordDracaena Cambodiana Agavaceae Homoisoflavonoid Cytotoxicity Cambodianol
DOI10.1080/10286020802674962
Indexed BySCI ; IC
Language英语
WOS Research AreaPlant Sciences ; Chemistry ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000263368000016
Citation statistics
Cited Times:24[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/1685
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming, Peoples R China
Recommended Citation
GB/T 7714
Liu, Jian,Mei, Wen-Li,Wu, Jiao,et al. A new cytotoxic homoisoflavonoid from Dracaena cambodiana[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2009,11(2):192-195.
APA Liu, Jian,Mei, Wen-Li,Wu, Jiao,Zhao, You-Xing,Peng, Ming,&Dai, Hao-Fu.(2009).A new cytotoxic homoisoflavonoid from Dracaena cambodiana.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,11(2),192-195.
MLA Liu, Jian,et al."A new cytotoxic homoisoflavonoid from Dracaena cambodiana".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 11.2(2009):192-195.
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