Two new compounds from Khaya senegalensis
Yuan, Chun-Mao1,2; Tang, Gui-Hua1; Wang, Xiao-Ying1; Zhang, Yu1; Guo, Feng1; Liao, Jin-Hua2; Zou, Tao2; Zuo, Guo-Ying3; Hua, Hui-Ming2; He, Hong-Ping1; Hao, Xiao-Jiang1
Corresponding AuthorHua, HM (reprint author), Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China. ; huimhua@163.com ; hehongping@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn
2013-06-01
Source PublicationJOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
ISSN1028-6020
Volume15Issue:6Pages:638-643
AbstractTwo new compounds, khayseneganin I (1) and 2,3,16-trihydroxy-20-acetoxy-20(R)-pregnane (2), along with six known compounds, 2,3,20-trihydroxy-16-acetoxy-20(R)-pregnane (3), 2,3-dihydroxypregnan-16-one-2,19-hemiketal (4), (+)-catechin (5), ivorenolide A (6), luteolin-7-O--l-rhamnoside (7), and (-)-5-methoxy-isolariciresinol-2a-O--d-xylopyranoside (8), were isolated from the leaves and twigs of Khaya senegalensis. The structures of new compounds were elucidated by 2D NMR spectroscopy and MS. Selected compounds (2-8) were evaluated for their antimicrobial activities and compounds 5 and 7 showed weak antimicrobial activities against MRSA 92(#) and MRSA 98(#).
KeywordKhaya Senegalensis Limonoid Steroid Antimicrobial Activitites
Subject AreaPlant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
Indexed BySCI ; IC
Language英语
WOS IDWOS:000320691600007
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/16769
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China
3.Chengdu Mil Command, Res Ctr Nat Med, Kunming Gen Hosp, Sch Clin, Kunming 650032, Peoples R China
Recommended Citation
GB/T 7714
Yuan, Chun-Mao,Tang, Gui-Hua,Wang, Xiao-Ying,et al. Two new compounds from Khaya senegalensis[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2013,15(6):638-643.
APA Yuan, Chun-Mao.,Tang, Gui-Hua.,Wang, Xiao-Ying.,Zhang, Yu.,Guo, Feng.,...&Hao, Xiao-Jiang.(2013).Two new compounds from Khaya senegalensis.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,15(6),638-643.
MLA Yuan, Chun-Mao,et al."Two new compounds from Khaya senegalensis".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 15.6(2013):638-643.
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