Synthesis of 3-[(Z)-Pentadec-8-enyl]catechol and Its Anti-angiogenesis Activity
Yang Mei1,3; He Jiangbo1; Cheng Yongxian1; Jiang Sheng2
2013-06-01
发表期刊CHINESE JOURNAL OF ORGANIC CHEMISTRY
ISSN0253-2786
卷号33期号:6页码:1319-1325
摘要3-[(Z)-Pentadec-8-enyl]catechol (GQ-5) was produced from 2,3-dimethoxybenzaldehyde through Barbier coupling reaction, the conversion of protecting group from methyl ether to acetonylidene, Wittig reaction and so on. These compounds have been confirmed by H-1 NMR, C-13 NMR and MS (or HRMS) techniques. Meanwhile, anti-angiogenesis activity of compound GQ-5 was evaluated by using HUVEC cells.
关键词Urushiol Resina Toxicodendri Wittig Reaction Angiogenesis
资助信息National Natural Science Foundation of China [U1202222]; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences [P2010-ZZ09]
学科领域Chemistry, Organic
收录类别SCI
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000322053600019
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/16765
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou 510530, Guangdong, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
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Yang Mei,He Jiangbo,Cheng Yongxian,et al. Synthesis of 3-[(Z)-Pentadec-8-enyl]catechol and Its Anti-angiogenesis Activity[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2013,33(6):1319-1325.
APA Yang Mei,He Jiangbo,Cheng Yongxian,&Jiang Sheng.(2013).Synthesis of 3-[(Z)-Pentadec-8-enyl]catechol and Its Anti-angiogenesis Activity.CHINESE JOURNAL OF ORGANIC CHEMISTRY,33(6),1319-1325.
MLA Yang Mei,et al."Synthesis of 3-[(Z)-Pentadec-8-enyl]catechol and Its Anti-angiogenesis Activity".CHINESE JOURNAL OF ORGANIC CHEMISTRY 33.6(2013):1319-1325.
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