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题名: Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy
作者: Yang, Yang1, 3; Yan, Yong-Ming1; Wei, Wei4; Luo, Jie1; Zhang, Lan-Sheng1; Zhou, Xiao-Jiang4; Wang, Peng-Cheng1; Yang, Yong-Xun2; null(程永现)1
刊名: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
关键词: Anthraquinone ; Oxanthrone C-glycoside ; Diabetic nephropathy ; Rumex ; Endophytic Aspergillus fumigatus
英文摘要: Two new oxanthrone C-glycosides, patientosides A (14) and B (15), together with three known ones (11-13), were isolated from Rumex patientia. Their structures were identified on the basis of spectroscopic methods. The absolute configuration for 14 and 15 were deduced by analysis of their CD spectra and comparison with those of known similar compounds. Compounds 11-15, and 14 known anthraquinones (1-4, 6-10, 16-20) previously isolated from Rumex nepalensis, Rumex hastatus, and endophytic Aspergillus fumigatus, respectively, as well as a commercially available compound rhein (5) were evaluated for their inhibitory effects on IL-6 and extracellular matrix production in mesangial cells. (c) 2013 Elsevier Ltd. All rights reserved.
出版日期: 2013-07-01
卷号: 23, 期号:13, 页码:3905-3909
语种: 英语
收录类别: SCI ; IC
学科分类: Chemistry, Medicinal; Chemistry, Organic
ISSN号: 0960-894X
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/16757
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
2.Chengdu Univ Tradit Chinese Med, Coll Pharm, Chengdu 610075, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
4.Hunan Univ Chinese Med, Coll Pharm, Changsha 410208, Hunan, Peoples R China

Recommended Citation:
Yang, Yang; Yan, Yong-Ming; Wei, Wei; Luo, Jie; Zhang, Lan-Sheng; Zhou, Xiao-Jiang; Wang, Peng-Cheng; Yang, Yong-Xun; Cheng, Yong-Xian.Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy,BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2013,23(13):3905-3909
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