Triterpenes from Tripterygium wilfordii Hook
Yang, J. -H.; Luo, S. -D.; Wang, Y-S.; Zhao, J. -F.; Zhang, H. -B.; Li, L.
2006-07-01
Source PublicationJOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
ISSN1028-6020
Volume8Issue:5Pages:425-429
AbstractTwo new friedelane-type triterpenes, tripterfrielanons A (1) and B (2), along with six known triterpenoids, friedelin (3), canophyllal (4), canophyltalic acid (5), 3-oxo-29-hydroxyfriedelane (6), wilforlide A (7), wilforlide B (8), have been isolated from the EtOH extract of the roots of Tripterygitan wilfordii Hook.f. Compounds 4, 5, 6 were isolated for the first time from this plant. The new triterpenes 1 and 2 exhibited mild cytotoxic activity against human Hela cell lines in vitro. The assay showed the IC50 of 1 and 2 were 8.5 and 25 mu g/mL, respectively.
KeywordTripterygium Wilfordii Hook.f Celastraceae Triterpenes Tripterfrielanons A-b
Subject AreaPlant Sciences ; Chemistry ; Applied ; Chemistry ; Medicinal ; Pharmacology & Pharmacy
DOI10.1080/10286020500172665
Indexed BySCI ; IC
Language英语
WOS Research AreaPlant Sciences ; Chemistry ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000239153600007
Citation statistics
Cited Times:17[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/1673
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Yunnan Univ, Ctr Adv Studies Med & Organ Chem, Sch Pharm, Kunming 650091, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources, Kunming 650204, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Yang, J. -H.,Luo, S. -D.,Wang, Y-S.,et al. Triterpenes from Tripterygium wilfordii Hook[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2006,8(5):425-429.
APA Yang, J. -H.,Luo, S. -D.,Wang, Y-S.,Zhao, J. -F.,Zhang, H. -B.,&Li, L..(2006).Triterpenes from Tripterygium wilfordii Hook.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,8(5),425-429.
MLA Yang, J. -H.,et al."Triterpenes from Tripterygium wilfordii Hook".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 8.5(2006):425-429.
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