Xinshengin (1), the first tetracyclic altenusin with an unprecedented altenuene/tetrahydrofuran-fused skeleton core, has been obtained from cultures of an endolichenic fungal strain Phialophora spp. (No. 39-1-5-1), along with a new compound, phialophoriol (2), and a known compound, altenusin (3). The structures with absolute configurations of 1 and 2 were elucidated by analysis of NMR and quantum chemical ECD calculation. (C) 2013 Elsevier Ltd. All rights reserved.
1.Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China 2.Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China 4.South China Agr Univ, Dept Pharmaceut Engn, Guangzhou 510642, Guangdong, Peoples R China
Recommended Citation:
Ye, Feng; Chen, Guo-Dong; He, Jun-Wei; Li, Xiao-Xia; Sun, Xiang; Guo, Liang-Dong; Li, Yan; Gao, Hao.Xinshengin, the first altenusin with tetracyclic skeleton core from Phialophora spp.,TETRAHEDRON LETTERS,2013,54(34):4551-4554
