Three new secoiridoids, swermacrolactones A-C and anti-hepatitis B virus activity from Swertia macrosperma
Wang, Hong-Ling1,2; Geng, Chang-An1; Ma, Yun-Bao1; Zhang, Xue-Mei1; Chen, Ji-Jun1
2013-09-01
发表期刊FITOTERAPIA
ISSN0367-326X
卷号89页码:183-187
摘要Three new secoiridoids, swermacrolactones A-C (1-3), together with fourteen known compounds were isolated from Swertia macrosperma. Their structures were elucidated based on extensive spectroscopic analyses (IR, UV, MS, 1D and 2D NMR). By anti-HBV assay on the Hep G 2.2.15 cell line in vitro, the most active compound, luteolin (9), inhibited the secretion of hepatitis B virus surface antigen (HBsAg) and hepatitis B virus e antigen (HBeAg) with IC50 values of 0.02 and 0.02 mM, respectively. (c) 2013 Elsevier B.V. All rights reserved.
关键词Secoiridoids Swermacrolactones A-c Anti-hbv Activity Swertia Macrosperma Gentianaceae
资助信息National Natural Science Foundation of China for Distinguished Young Scholars [81025023]; National Natural Science Foundation of China and Yunnan Province [U0832603]; West Light Foundation of the Chinese Academy of Sciences; International Foundation for Science, Stockholm, Sweden [F/5202-1]
学科领域Chemistry, Medicinal ; Pharmacology & Pharmacy
收录类别SCI
语种英语
WOS研究方向Pharmacology & Pharmacy
WOS类目Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000323856500020
引用统计
被引频次:15[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/16677
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714
Wang, Hong-Ling,Geng, Chang-An,Ma, Yun-Bao,et al. Three new secoiridoids, swermacrolactones A-C and anti-hepatitis B virus activity from Swertia macrosperma[J]. FITOTERAPIA,2013,89:183-187.
APA Wang, Hong-Ling,Geng, Chang-An,Ma, Yun-Bao,Zhang, Xue-Mei,&Chen, Ji-Jun.(2013).Three new secoiridoids, swermacrolactones A-C and anti-hepatitis B virus activity from Swertia macrosperma.FITOTERAPIA,89,183-187.
MLA Wang, Hong-Ling,et al."Three new secoiridoids, swermacrolactones A-C and anti-hepatitis B virus activity from Swertia macrosperma".FITOTERAPIA 89(2013):183-187.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Wang-2013-Three new (422KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Wang, Hong-Ling]的文章
[Geng, Chang-An]的文章
[Ma, Yun-Bao]的文章
百度学术
百度学术中相似的文章
[Wang, Hong-Ling]的文章
[Geng, Chang-An]的文章
[Ma, Yun-Bao]的文章
必应学术
必应学术中相似的文章
[Wang, Hong-Ling]的文章
[Geng, Chang-An]的文章
[Ma, Yun-Bao]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。