Khayseneganins A-H, Limonoids from Khaya senegalensis
Yuan, Chun-Mao1,2; Zhang, Yu1; Tang, Gui-Hua1; Di, Ying-Tong1; Cao, Ming-Ming1; Wang, Xiao-Ying1; Zuo, Guo-Ying3; Li, Shun-Lin1; Hua, Hui-Ming2; He, Hong-Ping1; Hao, Xiao-Jiang1
通讯作者Hua, HM (reprint author), Shenyang Pharmaceut Univ, Key Lab Struct Based Drug Design & Discovery, Minist Educ, Shenyang 110016, Peoples R China. ; haoxj@mail.kib.ac.cn
2013-03-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号76期号:3页码:327-333
摘要Eight new limonoids, khayseneganins A-H (1-8), and 31 known limonoids were isolated from the leaves and twigs of Khaya senegalensis. The structures of the new compounds were elucidated by 2D-NMR spectroscopy and mass spectrometry, and the absolute configuration of 1 was determined by the CD exciton chirality method. Compounds 9, 10, 12, and 15 showed antimicrobial activities against Pseudomonas aeruginosa, MRSA 92(#), and MRSA 98(#), all with a MIC value of 12.5 mu g/mL.
关键词Stem Bark Meliaceae Family Grandifoliola Khayanolides Ivorensis Ring Antifeedants Skeleton Leaves
学科领域Plant Sciences ; Pharmacology & Pharmacy
DOI10.1021/np3006919
收录类别SCI ; IC
语种英语
WOS记录号WOS:000316773900006
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/16447
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Peoples R China
2.Shenyang Pharmaceut Univ, Key Lab Struct Based Drug Design & Discovery, Minist Educ, Shenyang 110016, Peoples R China
3.Chengdu Mil Command, Res Ctr Nat Med, Sch Clin, Kunming Gen Hosp, Kunming 650032, Peoples R China
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Yuan, Chun-Mao,Zhang, Yu,Tang, Gui-Hua,et al. Khayseneganins A-H, Limonoids from Khaya senegalensis[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(3):327-333.
APA Yuan, Chun-Mao.,Zhang, Yu.,Tang, Gui-Hua.,Di, Ying-Tong.,Cao, Ming-Ming.,...&Hao, Xiao-Jiang.(2013).Khayseneganins A-H, Limonoids from Khaya senegalensis.JOURNAL OF NATURAL PRODUCTS,76(3),327-333.
MLA Yuan, Chun-Mao,et al."Khayseneganins A-H, Limonoids from Khaya senegalensis".JOURNAL OF NATURAL PRODUCTS 76.3(2013):327-333.
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