| Three new indole alkaloids from the leaves of Kopsia officinalis | |
Zhou, H; He, HP; Kong, NC; Wang, YH ; Liu, XD; Hao, XJ
| |
| 2006 | |
| Source Publication | HELVETICA CHIMICA ACTA
 |
| ISSN | 0018-019X |
| Volume | 89Issue:3Pages:515-519 |
| Abstract | Three new indole alkaloids, 11,12-de(methylenedioxy)danuphylline (1), methyl (2 beta,11 beta,12 beta,19 alpha)-6,7-didehydro-8,21-dioxo-11,21-cycloaspidospermidine-2-carboxylate (2), and (2 beta,5 beta)-aspidofractinin-16-ol (3) were isolated from Kopsia officinalis, together with 16 known compounds. Their structures were determined by spectroscopic methods. The isolated known compound (-)-12-methoxykopsinaline displayed antimanic effects in Drosophila, with an IC50 value of 12.5 mu g/ml. |
| Keyword | Dasyrachis Ridl Apocynaceae Drosophila |
| Subject Area | Chemistry ; Multidisciplinary |
| Indexed By | SCI ; IC |
| Language | 英语 |
| WOS ID | WOS:000236535500014 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/1629 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 10039, Peoples R China |
| Recommended Citation GB/T 7714 | Zhou, H,He, HP,Kong, NC,et al. Three new indole alkaloids from the leaves of Kopsia officinalis[J]. HELVETICA CHIMICA ACTA,2006,89(3):515-519. |
| APA | Zhou, H,He, HP,Kong, NC,Wang, YH,Liu, XD,&Hao, XJ.(2006).Three new indole alkaloids from the leaves of Kopsia officinalis.HELVETICA CHIMICA ACTA,89(3),515-519. |
| MLA | Zhou, H,et al."Three new indole alkaloids from the leaves of Kopsia officinalis".HELVETICA CHIMICA ACTA 89.3(2006):515-519. |
| Files in This Item: | Download All | |||||
| File Name/Size | DocType | Version | Access | License | ||
| 201111040003.pdf（283KB） | 开放获取 | -- | View Download | |||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment