Three new indole alkaloids from the leaves of Kopsia officinalis

	Three new indole alkaloids from the leaves of Kopsia officinalis
	Zhou, H ; He, HP ; Kong, NC ; Wang, YH; Liu, XD ; Hao, XJ
	2006
发表期刊	HELVETICA CHIMICA ACTA
ISSN	0018-019X
卷号	89 期号:3 页码:515-519
摘要	Three new indole alkaloids, 11,12-de(methylenedioxy)danuphylline (1), methyl (2 beta,11 beta,12 beta,19 alpha)-6,7-didehydro-8,21-dioxo-11,21-cycloaspidospermidine-2-carboxylate (2), and (2 beta,5 beta)-aspidofractinin-16-ol (3) were isolated from Kopsia officinalis, together with 16 known compounds. Their structures were determined by spectroscopic methods. The isolated known compound (-)-12-methoxykopsinaline displayed antimanic effects in Drosophila, with an IC50 value of 12.5 mu g/ml.
关键词	Dasyrachis Ridl Apocynaceae Drosophila
学科领域	Chemistry ; Multidisciplinary
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000236535500014
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/1629
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 10039, Peoples R China
推荐引用方式 GB/T 7714	Zhou, H,He, HP,Kong, NC,et al. Three new indole alkaloids from the leaves of Kopsia officinalis[J]. HELVETICA CHIMICA ACTA,2006,89(3):515-519.
APA	Zhou, H,He, HP,Kong, NC,Wang, YH,Liu, XD,&Hao, XJ.(2006).Three new indole alkaloids from the leaves of Kopsia officinalis.HELVETICA CHIMICA ACTA,89(3),515-519.
MLA	Zhou, H,et al."Three new indole alkaloids from the leaves of Kopsia officinalis".HELVETICA CHIMICA ACTA 89.3(2006):515-519.

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