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题名: Three new indole alkaloids from the leaves of Kopsia officinalis
作者: Zhou, H; He, HP; Kong, NC; Wang YueHu(王跃虎); Liu, XD; null(郝小江)
刊名: HELVETICA CHIMICA ACTA
关键词: DASYRACHIS RIDL ; APOCYNACEAE ; DROSOPHILA
英文摘要: Three new indole alkaloids, 11,12-de(methylenedioxy)danuphylline (1), methyl (2 beta,11 beta,12 beta,19 alpha)-6,7-didehydro-8,21-dioxo-11,21-cycloaspidospermidine-2-carboxylate (2), and (2 beta,5 beta)-aspidofractinin-16-ol (3) were isolated from Kopsia officinalis, together with 16 known compounds. Their structures were determined by spectroscopic methods. The isolated known compound (-)-12-methoxykopsinaline displayed antimanic effects in Drosophila, with an IC50 value of 12.5 mu g/ml.
出版日期: 2006
卷号: 89, 期号:3, 页码:515-519
语种: 英语
收录类别: SCI ; IC
学科分类: Chemistry; Multidisciplinary
ISSN号: 0018-019X
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/1629
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 10039, Peoples R China

Recommended Citation:
Zhou, H; He, HP; Kong, NC; Wang, YH; Liu, XD; Hao, XJ.Three new indole alkaloids from the leaves of Kopsia officinalis,HELVETICA CHIMICA ACTA,2006,89(3):515-519
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