A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii
Zhang, Yu-Mei1,2; Xu, Jian3; Xiao, Lin4; Zeng, Guang-Zhi1; Sun, Zhang-Hua3; Tan, Ning-Hua1
2013
发表期刊MOLECULES
ISSN1420-3049
卷号18期号:1页码:1255-1261
摘要A new phenolic glycoside, 3-methoxyphenol 1-O-alpha-L-rhamnopyranosyl-(1 -> 6)-O-beta-D-glucopyranoside (1), was isolated from the 90% acetone extract of the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii along with another 10 known phenolics 2-11. Their structures were determined mainly by means of MS, 1D- and 2D-NMR data. Cytotoxicities of compounds 3 and 5-11 were tested on BGC-823, Hela and A549 cancer cell lines, the results showed that compound 8 was bioactive and its IC50 values were 6.9, 29.7 and 52.9 mu M, respectively.
关键词Chamaecyparis Obtusa Var. Breviramea F. Crippsii Phenolic Compounds Cytotoxicity
资助信息National Natural Science Foundation of China [20972168, 30725048]; National New Drug Innovation Great Project of China [2011ZX09307-002-02]; Natural Science Foundation of Yunnan Province [2010CI048]; National Basic Research Program of China [2009CB522300]
学科领域Chemistry
收录类别SCI
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000314032900080
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/16206
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Heilongtan 650201, Kunming, Peoples R China
2.Chinese Acad Sci, Xishuanbanna Trop Bot Garden, Kunming 650223, Peoples R China
3.Hubei Univ Chinese Med, Fac Pharm, Key Lab, Minist Educ Tradit Chinese Med Resource & Compoun, Wuhan 430065, Peoples R China
4.Guangxi Univ, Coll Agr, Dept Plant Sci, Nanning 630004, Peoples R China
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GB/T 7714
Zhang, Yu-Mei,Xu, Jian,Xiao, Lin,et al. A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii[J]. MOLECULES,2013,18(1):1255-1261.
APA Zhang, Yu-Mei,Xu, Jian,Xiao, Lin,Zeng, Guang-Zhi,Sun, Zhang-Hua,&Tan, Ning-Hua.(2013).A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii.MOLECULES,18(1),1255-1261.
MLA Zhang, Yu-Mei,et al."A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii".MOLECULES 18.1(2013):1255-1261.
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