Phragmalin-type Limonoids from Heynea trijuga
Yang, Wei1,2; Kong, Lingmei1,2; Zhang, Yu1; Tang, Guihua1; Zhu, Feng1; Li, Shifei1; Guo, Lingli1; Cheng, Yuanyuan1; Hao, Xiaojiang1; He, Hongping1
Corresponding AuthorHao,XJ (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China.,
Source PublicationPLANTA MEDICA
AbstractNine new phragmalin-type limonoids, heytrijumalins A-I (1-9), together with the known 15-acetyltrichagmalin E (10) were isolated from the branches and leaves of Heynea trijuga. The structures of these new compounds were elucidated on the basis of extensive spectroscopic analysis. Compounds 6 and 10 showed insecticidal activity at 100 ppm, with corrected mortalities of 82.94% and 96.02%, respectively. Compounds 2 and 10 showed weak cytotoxicity against HL-60 and A-549 human tumor cell lines, with IC50 values ranging from 14.55 to 25.27 mu M.
KeywordHeynea Trijuga Meliaceae Phragmalin-type Limonoids Heytrijumalins A-i
Subject AreaPlant Sciences ; Medicinal ; Chemistry ; Pharmacology & Pharmacy
Indexed BySCI
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000310358400012
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Cited Times:7[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Yang, Wei,Kong, Lingmei,Zhang, Yu,et al. Phragmalin-type Limonoids from Heynea trijuga[J]. PLANTA MEDICA,2012,78(15):1676-1682.
APA Yang, Wei.,Kong, Lingmei.,Zhang, Yu.,Tang, Guihua.,Zhu, Feng.,...&He, Hongping.(2012).Phragmalin-type Limonoids from Heynea trijuga.PLANTA MEDICA,78(15),1676-1682.
MLA Yang, Wei,et al."Phragmalin-type Limonoids from Heynea trijuga".PLANTA MEDICA 78.15(2012):1676-1682.
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