Phragmalin-type Limonoids from Heynea trijuga
Yang, Wei1,2; Kong, Lingmei1,2; Zhang, Yu1; Tang, Guihua1; Zhu, Feng1; Li, Shifei1; Guo, Lingli1; Cheng, Yuanyuan1; Hao, Xiaojiang1; He, Hongping1
2012-10-01
发表期刊PLANTA MEDICA
ISSN0032-0943
卷号78期号:15页码:1676-1682
摘要Nine new phragmalin-type limonoids, heytrijumalins A-I (1-9), together with the known 15-acetyltrichagmalin E (10) were isolated from the branches and leaves of Heynea trijuga. The structures of these new compounds were elucidated on the basis of extensive spectroscopic analysis. Compounds 6 and 10 showed insecticidal activity at 100 ppm, with corrected mortalities of 82.94% and 96.02%, respectively. Compounds 2 and 10 showed weak cytotoxicity against HL-60 and A-549 human tumor cell lines, with IC50 values ranging from 14.55 to 25.27 mu M.
关键词Heynea Trijuga Meliaceae Phragmalin-type Limonoids Heytrijumalins A-i
资助信息National Basic Research Program of China (973 Program) [2009CB522300, 2009CB940900]; National Natural Science Funding of China [31170332]; National New Drug Innovation Major Project of China [2011ZX09307-002-02]; Young Academic and Technical Leader Raising Foundation of Yunnan Province [2010CI047]
学科领域Plant Sciences ; Medicinal ; Chemistry ; Pharmacology & Pharmacy
DOI10.1055/s-0032-1315210
收录类别SCI
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000310358400012
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/15946
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
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Yang, Wei,Kong, Lingmei,Zhang, Yu,et al. Phragmalin-type Limonoids from Heynea trijuga[J]. PLANTA MEDICA,2012,78(15):1676-1682.
APA Yang, Wei.,Kong, Lingmei.,Zhang, Yu.,Tang, Guihua.,Zhu, Feng.,...&He, Hongping.(2012).Phragmalin-type Limonoids from Heynea trijuga.PLANTA MEDICA,78(15),1676-1682.
MLA Yang, Wei,et al."Phragmalin-type Limonoids from Heynea trijuga".PLANTA MEDICA 78.15(2012):1676-1682.
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