| Zizimauritic acids A-C, three novel nortriterpenes from Ziziphus mauritiana | |
| Ji, Chang-Jiu1,2; Zeng, Guang-Zhi1; Han, Jing1,2; He, Wen-Jun1; Zhang, Yu-Mei1; Tan, Ning-Hua1 | |
| 通讯作者 | Tan, NH (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunnan, Peoples R China.,nhtan@mail.kib.ac.cn |
| 2012-10-15 | |
| 发表期刊 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
 |
| ISSN | 0960-894X |
| 卷号 | 22期号:20页码:6377-6380 |
| 摘要 | Zizimauritic acids A-C (1-3), three novel nortriterpenes with a unique A-nor-E-seco spiro-lactone ceanothane-type triterpene skeleton, together with 3 known triterpenes ceanothenic acid (4), betulinic acid (5), and ceanothic acid (6), were isolated from the roots of Ziziphus mauritiana. Compounds 1-4 showed cytotoxicities with the IC50 values ranging from 5.05 to 11.94 mu g/ml, and compounds 1 and 3 showed an inhibitory effect on the growth of Staphylococcus aureus with the IC50 values 2.17 and 12.79 mu g/ml. A plausible biosynthetic pathway of compounds 1-3 was proposed. (c) 2012 Elsevier Ltd. All rights reserved. |
| 关键词 | Ziziphus Mauritiana Nortriterpene Zizimauritic Acids A-c Cytotoxicity Antibacterial Activity |
| 学科领域 | Chemistry, Medicinal ; Chemistry, Organic |
| DOI | 10.1016/j.bmcl.2012.08.074 |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000309609500013 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/15938 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ji, Chang-Jiu,Zeng, Guang-Zhi,Han, Jing,et al. Zizimauritic acids A-C, three novel nortriterpenes from Ziziphus mauritiana[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2012,22(20):6377-6380. |
| APA | Ji, Chang-Jiu,Zeng, Guang-Zhi,Han, Jing,He, Wen-Jun,Zhang, Yu-Mei,&Tan, Ning-Hua.(2012).Zizimauritic acids A-C, three novel nortriterpenes from Ziziphus mauritiana.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,22(20),6377-6380. |
| MLA | Ji, Chang-Jiu,et al."Zizimauritic acids A-C, three novel nortriterpenes from Ziziphus mauritiana".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 22.20(2012):6377-6380. |
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