3,4-seco-Diterpenoids from Trigonostemon flavidus | |
Tang, Gui-Hua1,2![]() ![]() ![]() ![]() ![]() | |
Corresponding Author | Zhang, Y (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China.,zhangyu@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn |
2012-11-25 | |
Source Publication | TETRAHEDRON
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ISSN | 0040-4020 |
Volume | 68Issue:47Pages:9679-9684 |
Abstract | Phytochemical investigation on the stems of Trigonostemon flavidus resulted in the isolation of five new 3,4-seco-diterpenoids, trigoflavidones A-E (1-5), structurally related to the main co-occurring known 3,4-seco-sonderianic acid (6) and 3,4-seco-sonderianol (7). Compound 4 possesses new 3,4-seco rearranged ent-pimarane skeletal type, characteristic of a vinyl group at C-8, while 5 features a unique five-membered ring (C-1) fused with a cyclopropane ring (C-2). The structures of the new compounds were established by a combination of spectroscopic data and computational methods. Compounds 1-7 were tested for their cytotoxicities on HL-60, SMMC-7721, A-549, MCF-7, and SW480 human tumor cell lines. (c) 2012 Elsevier Ltd. All rights reserved. |
Keyword | Euphorbiaceae Trigonostemon Flavidus Trigoflavidones A-e 3 4-seco-diterpenoids |
Subject Area | Chemistry, Organic |
DOI | 10.1016/j.tet.2012.09.052 |
Indexed By | SCI ; IC |
Language | 英语 |
WOS ID | WOS:000310402400021 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.kib.ac.cn/handle/151853/15908 |
Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England 4.Chinese Acad Sci, Kunming Inst Bot, Key Lab Econ Plants & Biotechnol, Kunming 650201, Peoples R China |
Recommended Citation GB/T 7714 | Tang, Gui-Hua,He, Hong-Ping,Gu, Yu-Cheng,et al. 3,4-seco-Diterpenoids from Trigonostemon flavidus[J]. TETRAHEDRON,2012,68(47):9679-9684. |
APA | Tang, Gui-Hua.,He, Hong-Ping.,Gu, Yu-Cheng.,Di, Ying-Tong.,Wang, Yue-Hu.,...&Hao, Xiao-Jiang.(2012).3,4-seco-Diterpenoids from Trigonostemon flavidus.TETRAHEDRON,68(47),9679-9684. |
MLA | Tang, Gui-Hua,et al."3,4-seco-Diterpenoids from Trigonostemon flavidus".TETRAHEDRON 68.47(2012):9679-9684. |
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