| Gelsemium alkaloids, immunosuppressive agents from Gelsemium elegans | |
Xu, You-Kai1; Liao, Shang-Gao2; Na, Zhi3; Hu, Hua-Bin1; Li, Yan4 ; Luo, Huai-Rong4
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| 通讯作者 | Xu, YK (reprint author), Chinese Acad Sci, Xishuangbanna Trop Bot Garden, CAS Key Lab Trop Forest Ecol, Mengla 666303, Yunnan Province, Peoples R China.,xyk@xtbg.ac.cn ; lshangg@163.com |
| 2012-09-01 | |
| 发表期刊 | FITOTERAPIA
 |
| ISSN | 0367-326X |
| 卷号 | 83期号:6页码:1120-1124 |
| 摘要 | Bioassay-guided isolation of the stems of Gelsemium elegans has led to the isolation of two new Gelsemium alkaloids, 21-(2-oxopropyl)-koumine (1) and 11-methoxygelselegine (2), and two known alkaloids, koumine (3) and gelselegine (4). The structures of 1-2 were determined by spectroscopic (for both) and single-crystal X-ray diffraction (for 1) analysis. All compounds isolated were evaluated for their potential as immunosuppressive agents and the data suggested that Gelsemium alkaloids of different structural types possibly have potential as immunosuppressive agents. (C) 2012 Elsevier B.V. All rights reserved. |
| 关键词 | Gelsemium Elegant 21-(2-oxopropyl)-koumine 11-methoxygelselegine Immunosuppressive Activity |
| DOI | 10.1016/j.fitote.2012.04.023 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000308116600024 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/15708 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Xishuangbanna Trop Bot Garden, CAS Key Lab Trop Forest Ecol, Mengla 666303, Yunnan Province, Peoples R China 2.Guiyang Med Coll, Sch Pharm, Guiyang 550004, Peoples R China 3.Chinese Acad Sci, Lab Trop Plant Resource Sci, Xishuangbanna Trop Bot Garden, Mengla 666303, Yunnan Province, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, You-Kai,Liao, Shang-Gao,Na, Zhi,et al. Gelsemium alkaloids, immunosuppressive agents from Gelsemium elegans[J]. FITOTERAPIA,2012,83(6):1120-1124. |
| APA | Xu, You-Kai,Liao, Shang-Gao,Na, Zhi,Hu, Hua-Bin,Li, Yan,&Luo, Huai-Rong.(2012).Gelsemium alkaloids, immunosuppressive agents from Gelsemium elegans.FITOTERAPIA,83(6),1120-1124. |
| MLA | Xu, You-Kai,et al."Gelsemium alkaloids, immunosuppressive agents from Gelsemium elegans".FITOTERAPIA 83.6(2012):1120-1124. |
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