Two new abietane diterpenoids from Salvia yunnanensis

doi:10.1055/s-2005-873184

	Two new abietane diterpenoids from Salvia yunnanensis
	Xu, G; Peng, LY ; Lu, L ; Weng, ZY ; Zhao, Y ; Li, XL ; Zhao, QS; Sun, HD
通讯作者	Zhao, QS (reprint author), Chinese Acad Sci, Kunming Ints Bot, State Key Lab Phytochem & Plant Resources W China, Heilongtan, Kunming 650204, Peoples R China. qinshizhaosp@yahoo.com
	2006
发表期刊	PLANTA MEDICA
ISSN	0032-0943
卷号	72 期号:1 页码:84-86
摘要	Two new abietane diterpenoids, yunnannin A (1) and danshenol C (2), were isolated from Salvia yunnanensis together with ten known diterpenoids, danshenol A (3), przewalskin (4), tanshinone IIA, tanshinone I, crypotanshinone, 1,2-dihydrotanshinone, tanshinlactone, 5,6-dehydrosugiol, 12-hydroxy-6,7-seco-8,11,3-abietatriene-6,7-dial and phytol. Their structures were established based on spectroscopic data, chemical reactions and comparison with literature data. Compounds 1-3 were tested for their antitumor activity in T-24, QGY, K562, Me180 and BIU87 cell lines. Compound 3 showed inhibited growth of K562 (IC50 = 0.53 mu g/mL), T-24 (IC50 = 7.94 mu g/mL), QGY (IC50 = 4.65 mu g/mL) and Me180 (IC50 = 6.89 mu g/mL) cell lines while compound 2 was inactive. Compound 1 showed moderate inhibitory activity on QGY (IC50 = 16.75 mu g/mL) and Me180 (IC50 = 5.84 mu g/ mL) cells.
关键词	Miltiorrhiza Tanshinones Bunge
学科领域	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI	10.1055/s-2005-873184
收录类别	SCI
语种	英语
WOS记录号	WOS:000235605700019
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/15432
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Ints Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Guiyang Med Coll, Guiyang, Peoples R China
推荐引用方式 GB/T 7714	Xu, G,Peng, LY,Lu, L,et al. Two new abietane diterpenoids from Salvia yunnanensis[J]. PLANTA MEDICA,2006,72(1):84-86.
APA	Xu, G.,Peng, LY.,Lu, L.,Weng, ZY.,Zhao, Y.,...&Sun, HD.(2006).Two new abietane diterpenoids from Salvia yunnanensis.PLANTA MEDICA,72(1),84-86.
MLA	Xu, G,et al."Two new abietane diterpenoids from Salvia yunnanensis".PLANTA MEDICA 72.1(2006):84-86.

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