Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B

doi:10.1007/s11426-005-0204-5

	Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B
	Jia, AQ ; Li, X ; Tan, NH ; Liu, XZ ; Shen, YM ; Zhou, J
通讯作者	Zhou, J (reprint author), Grad Univ Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China. jzhou@mail.kib.ac.cn
	2006-02-01
发表期刊	SCIENCE IN CHINA SERIES B-CHEMISTRY
ISSN	1006-9291
卷号	49 期号:1 页码:63-66
摘要	The crude enzyme (PH-1) isolated from Pseudostellaria heterophylla by our group has catalyzed enzymatic cyclization of linear peptide NH2-Gly(1)-GlY(2)-Leu-Pro-Pro-Pro-lle-Phe-COOH (4) into cyclopeptide heterophyllin B (HB) from plant for the first time. To ensure this reaction, some analytical methods including TLC, HPLC, MS, NMR, and C-13 labeling were used to prove that the reaction of substrate 4 sharing residue of NH-Phe-Gly-CO was successful.
关键词	Pseudostellaria Heterophylla Cyclopeptides Hb Enzymatic Cyclization Isotope Labeled
学科领域	Chemistry, Multidisciplinary
DOI	10.1007/s11426-005-0204-5
收录类别	SCI
语种	英语
WOS记录号	WOS:000236156000005
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/15430
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Grad Univ Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Peptide Co Ltd, Hangzhou 310018, Peoples R China 3.SW Forestry Coll, Kunming 650204, Peoples R China
推荐引用方式 GB/T 7714	Jia, AQ,Li, X,Tan, NH,et al. Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,2006,49(1):63-66.
APA	Jia, AQ,Li, X,Tan, NH,Liu, XZ,Shen, YM,&Zhou, J.(2006).Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B.SCIENCE IN CHINA SERIES B-CHEMISTRY,49(1),63-66.
MLA	Jia, AQ,et al."Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B".SCIENCE IN CHINA SERIES B-CHEMISTRY 49.1(2006):63-66.

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