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题名: Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B
作者: Jia, AQ; Li, X; Tan, NH; Liu, XZ; Shen, YM; Zhou, J
刊名: SCIENCE IN CHINA SERIES B-CHEMISTRY
关键词: Pseudostellaria heterophylla ; cyclopeptides ; HB ; enzymatic cyclization ; isotope labeled
英文摘要: The crude enzyme (PH-1) isolated from Pseudostellaria heterophylla by our group has catalyzed enzymatic cyclization of linear peptide NH2-Gly(1)-GlY(2)-Leu-Pro-Pro-Pro-lle-Phe-COOH (4) into cyclopeptide heterophyllin B (HB) from plant for the first time. To ensure this reaction, some analytical methods including TLC, HPLC, MS, NMR, and C-13 labeling were used to prove that the reaction of substrate 4 sharing residue of NH-Phe-Gly-CO was successful.
出版日期: 2006-02-01
卷号: 49, 期号:1, 页码:63-66
语种: 英语
收录类别: SCI
学科分类: Chemistry, Multidisciplinary
ISSN号: 1006-9291
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/15430
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Grad Univ Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Peptide Co Ltd, Hangzhou 310018, Peoples R China
3.SW Forestry Coll, Kunming 650204, Peoples R China

Recommended Citation:
Jia, AQ; Li, X; Tan, NH; Liu, XZ; Shen, YM; Zhou, J.Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B,SCIENCE IN CHINA SERIES B-CHEMISTRY,2006,49(1):63-66
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