Three new C-21-steroidal glycosides presenting an unusual 13,14:14,15-disecopregnane-type skeleton, named inamosides A-C (1-3), together with two known C-21-steroidal glycosides, were isolated from the MeOH extract of the roots of Cynanchum inamoeum (Maxim.) Loes (Asclepiadaceae). The aglycone of compounds 1, 2, and 3 has a 2-hydroxyl, which has not yet been reported in the literature. The structure and relative configuration of the aglycone of compounds 1, 2, and 3 were established by X-ray crystallographic analysis.
1.Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Yunnan Normal Univ, Sch Chem & Engn, Kunming 650092, Peoples R China 3.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
Recommended Citation:
Wang, LQ; Lu, Y; Zhao, YX; Zhou, J; Zheng, QT.Three new C-21-steroidal glycosides from the roots of Cynanchum inamoenum,JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2007,9(8):771-779
