Antiproliferative ent-kauranoids from Isodon parvifolius | |
Li, Li-Mei; Li, Guo-You; Huang, Sheng-Xiong; Xiao, Wei-Lie; Liao, Xun; Lou, Li-Guang; Ding, Li-Sheng; Sun, Han-Dong | |
通讯作者 | Sun, HD (reprint author), Chinese Acad Sci, Kunming Inst Biol, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China. hdsun@mail.kib.ac.cn |
2006-06-01 | |
发表期刊 | PLANTA MEDICA |
ISSN | 0032-0943 |
卷号 | 72期号:8页码:740-745 |
摘要 | Nine new 7 alpha,20-epoxy-ent-kaurane diterpenoids, parvifolines O - W (1-9), together with five known analogues, lasiocarpanin (10), rosthorin A (11), longikaurin E (12), adenolin D (13) and longikaurin B (14), were isolated from the leaves of Isodon parvifolius. Their structures were determined by means of spectroscopic analysis. Selected diterpenoids (1-10) were tested for their antiproliferative activity against A549, HT-29 and K562 cells. Compounds 3, 7, 8 and 10 showed moderate inhibitory activity against all three cell lines. |
关键词 | Isodon Parvifolius Labiatae Diterpenoids Ent-kauranes Parvifolines O-w Antiproliferative Activity |
学科领域 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
DOI | 10.1055/s-2006-931608 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000239243200012 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/15424 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Biol, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Inst Biol, Chengdu, Peoples R China 3.Chinese Acad Sci, Inst Biol Sci, Shanghai Inst Mat Med, Shanghai, Peoples R China 4.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Li-Mei,Li, Guo-You,Huang, Sheng-Xiong,et al. Antiproliferative ent-kauranoids from Isodon parvifolius[J]. PLANTA MEDICA,2006,72(8):740-745. |
APA | Li, Li-Mei.,Li, Guo-You.,Huang, Sheng-Xiong.,Xiao, Wei-Lie.,Liao, Xun.,...&Sun, Han-Dong.(2006).Antiproliferative ent-kauranoids from Isodon parvifolius.PLANTA MEDICA,72(8),740-745. |
MLA | Li, Li-Mei,et al."Antiproliferative ent-kauranoids from Isodon parvifolius".PLANTA MEDICA 72.8(2006):740-745. |
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