Antiproliferative ent-kauranoids from Isodon parvifolius
Li, Li-Mei; Li, Guo-You; Huang, Sheng-Xiong; Xiao, Wei-Lie; Liao, Xun; Lou, Li-Guang; Ding, Li-Sheng; Sun, Han-Dong
通讯作者Sun, HD (reprint author), Chinese Acad Sci, Kunming Inst Biol, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China. hdsun@mail.kib.ac.cn
2006-06-01
发表期刊PLANTA MEDICA
ISSN0032-0943
卷号72期号:8页码:740-745
摘要Nine new 7 alpha,20-epoxy-ent-kaurane diterpenoids, parvifolines O - W (1-9), together with five known analogues, lasiocarpanin (10), rosthorin A (11), longikaurin E (12), adenolin D (13) and longikaurin B (14), were isolated from the leaves of Isodon parvifolius. Their structures were determined by means of spectroscopic analysis. Selected diterpenoids (1-10) were tested for their antiproliferative activity against A549, HT-29 and K562 cells. Compounds 3, 7, 8 and 10 showed moderate inhibitory activity against all three cell lines.
关键词Isodon Parvifolius Labiatae Diterpenoids Ent-kauranes Parvifolines O-w Antiproliferative Activity
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1055/s-2006-931608
收录类别SCI
语种英语
WOS记录号WOS:000239243200012
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/15424
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Biol, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Inst Biol, Chengdu, Peoples R China
3.Chinese Acad Sci, Inst Biol Sci, Shanghai Inst Mat Med, Shanghai, Peoples R China
4.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
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Li, Li-Mei,Li, Guo-You,Huang, Sheng-Xiong,et al. Antiproliferative ent-kauranoids from Isodon parvifolius[J]. PLANTA MEDICA,2006,72(8):740-745.
APA Li, Li-Mei.,Li, Guo-You.,Huang, Sheng-Xiong.,Xiao, Wei-Lie.,Liao, Xun.,...&Sun, Han-Dong.(2006).Antiproliferative ent-kauranoids from Isodon parvifolius.PLANTA MEDICA,72(8),740-745.
MLA Li, Li-Mei,et al."Antiproliferative ent-kauranoids from Isodon parvifolius".PLANTA MEDICA 72.8(2006):740-745.
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