Two new lanostanoids from Ganoderma resinaceum | |
Niu, Xue-Mei1,2; Li, Sheng-Hong2; Xiao, Wei-Lie2; Sun, Han-Dong2; Che, Chun-Tao1 | |
2007 | |
发表期刊 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH |
ISSN | 1028-6020 |
卷号 | 9期号:7页码:659-664 |
摘要 | Two new lanostane triterpenoids, 3-epipachymic acid (3-acetoxy-16 alpha-hydroxy-24-methylene-5 alpha-lanost-8-en-21-oic acid, 1) and 3 alpha-(3-hydroxy-5-methoxy-3-methyl-1,5-dioxopentyloxy)-24-methylene-5 alpha-lanost-8-en-21-oic acid (2), together with a known compound, 3-oxo-5 alpha-lanosta-8,24-dien-21-oic acid (3), were isolated from the fruiting body of Ganoderma resinaceum. The structure elucidation was accomplished by spectroscopic methods, especially NMR experiments. Compound 2 showed significant cytotoxic activity with IC50 value of 2.5 mu g/ml in Hep-2 cell line. |
关键词 | Lanostane Triterpenoids Ganoderma Resinaceum Lingzhi Cytotoxicity |
学科领域 | Plant Sciences ; Chemistry ; Applied ; Chemistry ; Medicinal ; Pharmacology & Pharmacy |
DOI | 10.1080/10286020600979910 |
收录类别 | SCI ; IC |
语种 | 英语 |
WOS记录号 | WOS:000253300400012 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/1535 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Univ Hong Kong, Sch Chinese Med, Shatin, Hong Kong, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China |
推荐引用方式 GB/T 7714 | Niu, Xue-Mei,Li, Sheng-Hong,Xiao, Wei-Lie,et al. Two new lanostanoids from Ganoderma resinaceum[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2007,9(7):659-664. |
APA | Niu, Xue-Mei,Li, Sheng-Hong,Xiao, Wei-Lie,Sun, Han-Dong,&Che, Chun-Tao.(2007).Two new lanostanoids from Ganoderma resinaceum.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,9(7),659-664. |
MLA | Niu, Xue-Mei,et al."Two new lanostanoids from Ganoderma resinaceum".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 9.7(2007):659-664. |
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