Two new lanostanoids from Ganoderma resinaceum
Niu, Xue-Mei1,2; Li, Sheng-Hong2; Xiao, Wei-Lie2; Sun, Han-Dong2; Che, Chun-Tao1
2007
发表期刊JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
ISSN1028-6020
卷号9期号:7页码:659-664
摘要Two new lanostane triterpenoids, 3-epipachymic acid (3-acetoxy-16 alpha-hydroxy-24-methylene-5 alpha-lanost-8-en-21-oic acid, 1) and 3 alpha-(3-hydroxy-5-methoxy-3-methyl-1,5-dioxopentyloxy)-24-methylene-5 alpha-lanost-8-en-21-oic acid (2), together with a known compound, 3-oxo-5 alpha-lanosta-8,24-dien-21-oic acid (3), were isolated from the fruiting body of Ganoderma resinaceum. The structure elucidation was accomplished by spectroscopic methods, especially NMR experiments. Compound 2 showed significant cytotoxic activity with IC50 value of 2.5 mu g/ml in Hep-2 cell line.
关键词Lanostane Triterpenoids Ganoderma Resinaceum Lingzhi Cytotoxicity
学科领域Plant Sciences ; Chemistry ; Applied ; Chemistry ; Medicinal ; Pharmacology & Pharmacy
DOI10.1080/10286020600979910
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000253300400012
引用统计
被引频次:19[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/1535
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Univ Hong Kong, Sch Chinese Med, Shatin, Hong Kong, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
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GB/T 7714
Niu, Xue-Mei,Li, Sheng-Hong,Xiao, Wei-Lie,et al. Two new lanostanoids from Ganoderma resinaceum[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2007,9(7):659-664.
APA Niu, Xue-Mei,Li, Sheng-Hong,Xiao, Wei-Lie,Sun, Han-Dong,&Che, Chun-Tao.(2007).Two new lanostanoids from Ganoderma resinaceum.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,9(7),659-664.
MLA Niu, Xue-Mei,et al."Two new lanostanoids from Ganoderma resinaceum".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 9.7(2007):659-664.
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