Mekongenines A and B, two new alkaloids from Bousigonia mekongensis

doi:10.1016/j.tetlet.2012.05.026

	Mekongenines A and B, two new alkaloids from Bousigonia mekongensis
	Fu, Yanhui1,2 ; He, Hongping 1; Di, Yingtong1 ; Li, Shunlin 1; Zhang, Yu1 ; Hao, Xiaojiang1
通讯作者	Zhang, Y (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China. ; zhangyu@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn
	2012-07-11
发表期刊	TETRAHEDRON LETTERS
ISSN	0040-4039
卷号	53 期号:28 页码:3642-3646
摘要	Mekongenine A (1) possessing an unprecedented structure constituted from the union of a rare 2,7-seco eburnamine half and an aspidospermine alkaloid, together with a new bisindole alkaloid, mekongenine B (2), consisting of an eburnamine-aspidospennine type skeleton, was isolated from Bousigonia mekongensis. Their structures were elucidated by means of spectroscopic methods and those of 2 were further confirmed by X-ray diffraction. The absolute configurations of 1 and 2 were determined by comparison of quantum chemical TDDFT calculated and experimental ECD spectra. Mekongenines A (1) and B(2) exhibited cell growth inhibitory activities against various human cancer cell lines. (C) 2012 Elsevier Ltd. All rights reserved.
关键词	Bousigonia Mekongensis Alkaloids Mekongenine a Mekongenine b
学科领域	Chemistry, Organic
DOI	10.1016/j.tetlet.2012.05.026
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000305856100025
引用统计	被引频次：27[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/15077
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Fu, Yanhui,He, Hongping,Di, Yingtong,et al. Mekongenines A and B, two new alkaloids from Bousigonia mekongensis[J]. TETRAHEDRON LETTERS,2012,53(28):3642-3646.
APA	Fu, Yanhui,He, Hongping,Di, Yingtong,Li, Shunlin,Zhang, Yu,&Hao, Xiaojiang.(2012).Mekongenines A and B, two new alkaloids from Bousigonia mekongensis.TETRAHEDRON LETTERS,53(28),3642-3646.
MLA	Fu, Yanhui,et al."Mekongenines A and B, two new alkaloids from Bousigonia mekongensis".TETRAHEDRON LETTERS 53.28(2012):3642-3646.

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