Mekongenines A and B, two new alkaloids from Bousigonia mekongensis
Fu, Yanhui1,2; He, Hongping1; Di, Yingtong1; Li, Shunlin1; Zhang, Yu1; Hao, Xiaojiang1
2012-07-11
发表期刊TETRAHEDRON LETTERS
ISSN0040-4039
卷号53期号:28页码:3642-3646
摘要Mekongenine A (1) possessing an unprecedented structure constituted from the union of a rare 2,7-seco eburnamine half and an aspidospermine alkaloid, together with a new bisindole alkaloid, mekongenine B (2), consisting of an eburnamine-aspidospennine type skeleton, was isolated from Bousigonia mekongensis. Their structures were elucidated by means of spectroscopic methods and those of 2 were further confirmed by X-ray diffraction. The absolute configurations of 1 and 2 were determined by comparison of quantum chemical TDDFT calculated and experimental ECD spectra. Mekongenines A (1) and B(2) exhibited cell growth inhibitory activities against various human cancer cell lines. (C) 2012 Elsevier Ltd. All rights reserved.
关键词Bousigonia Mekongensis Alkaloids Mekongenine a Mekongenine b
资助信息National Natural Science Foundation of China[31100259, 30830114]; National Basic Research Program of China[2009CB940900, 2009CB522303]; Young Academic and Technical Leader Raising Foundation of Yunnan Province[2009CI072]
收录类别SCI ; IC
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/15077
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
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Fu, Yanhui,He, Hongping,Di, Yingtong,et al. Mekongenines A and B, two new alkaloids from Bousigonia mekongensis[J]. TETRAHEDRON LETTERS,2012,53(28):3642-3646.
APA Fu, Yanhui,He, Hongping,Di, Yingtong,Li, Shunlin,Zhang, Yu,&Hao, Xiaojiang.(2012).Mekongenines A and B, two new alkaloids from Bousigonia mekongensis.TETRAHEDRON LETTERS,53(28),3642-3646.
MLA Fu, Yanhui,et al."Mekongenines A and B, two new alkaloids from Bousigonia mekongensis".TETRAHEDRON LETTERS 53.28(2012):3642-3646.
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