Four New ent-Kauranoids from Isodon rubescens var. lushanensis and Data Reassignment of Dayecrystal B
Zhang, Ha-Bo1,2; Pu, Jian-Xin1; Wang, Yuan-Yuan1; He, Fei1,2; Zhao, Yong1; Li, Xiao-Nian1,2; Luo, Xiao1,2; Xiao, Wei-Lie1; Li, Yan1; Sun, Han-Dong1
2010
Source PublicationCHEMICAL & PHARMACEUTICAL BULLETIN
ISSN0009-2363
Volume58Issue:1Pages:56-60
AbstractFour new 7, 20-epoxy-ent-kauranoids, rubluanins A-D (1-4) and eleven known ones, were isolated from Isodon rubescens var. lushanensis, and their structures were elucidated by spectroscopic analysis. Compounds 2-14 were evaluated for their cytotoxicity in several human tumor cell lines (U937, Jurkat, HL-60, K562, SGC790, and HepG2). Among the compounds, lasiokaurin (13) showed significant cytotoxic activity of 0.62 mu M (IC50) in U937 cells.
KeywordIsodon Rubescens Var. Lushanensis Ent-kauranoid Cytotoxicity
Subject AreaChemistry ; Medicinal ; Multidisciplinary ; Chemistry ; Pharmacology & Pharmacy
Indexed BySCI ; IC
Language英语
WOS Research AreaPharmacology & Pharmacy ; Chemistry
WOS SubjectChemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
WOS IDWOS:000273168400011
Citation statistics
Cited Times:6[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/1503
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Ha-Bo,Pu, Jian-Xin,Wang, Yuan-Yuan,et al. Four New ent-Kauranoids from Isodon rubescens var. lushanensis and Data Reassignment of Dayecrystal B[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2010,58(1):56-60.
APA Zhang, Ha-Bo.,Pu, Jian-Xin.,Wang, Yuan-Yuan.,He, Fei.,Zhao, Yong.,...&Sun, Han-Dong.(2010).Four New ent-Kauranoids from Isodon rubescens var. lushanensis and Data Reassignment of Dayecrystal B.CHEMICAL & PHARMACEUTICAL BULLETIN,58(1),56-60.
MLA Zhang, Ha-Bo,et al."Four New ent-Kauranoids from Isodon rubescens var. lushanensis and Data Reassignment of Dayecrystal B".CHEMICAL & PHARMACEUTICAL BULLETIN 58.1(2010):56-60.
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