Cytotoxic steroidal saponins from Polygonatum punctatum

	Cytotoxic steroidal saponins from Polygonatum punctatum
	Yang, Qing-Xiong ; Yang, Chong-Ren
	2006
发表期刊	CHEMISTRY & BIODIVERSITY
ISSN	1612-1872
卷号	3 期号:12 页码:1349-1355
摘要	Four new steroidal saponins, polypunctosides A-D (1-4, resp.), were isolated from the rhizomes of Polygonatum punctatum, together with five known steroidal saponins. On the basis of chemical and spectral evidence, the structures of the new saponins were established as (3 beta,23S,25R)-23-(alpha-L-arabinopyranosyloxy)spirost-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-D-glucopyranoside (1), (3 beta,23S,25R)-23-[ (2-O-acetyl-alpha-L-arabinopyranosyl)oxy]spirost-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-D-glucopyranoside (2), (3 beta,23S,25R)-23-[(3-O-acetyl-alpha-L-arabinopyranosyl)oxy]spirost-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-D-glucopyranoside (3), and (3 beta,23S,25R)-23-[(4-O-acetyl-alpha-L-arabinopyranosyl)oxy]spirost-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-D-glucopyranoside (4). The cytotoxic activity of the isolated saponins was evaluated towards HeLa cells.
关键词	Ophiopogonis Tuber Subterranean Part Constituents Congeners
学科领域	Biochemistry & Molecular Biology ; Chemistry ; Multidisciplinary
收录类别	SCI
语种	英语
WOS记录号	WOS:000243372200007
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/1481
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Guizhou Normal Univ, Coll Biotechnol & Bioengn, Guiyang 550001, Peoples R China 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
推荐引用方式 GB/T 7714	Yang, Qing-Xiong,Yang, Chong-Ren. Cytotoxic steroidal saponins from Polygonatum punctatum[J]. CHEMISTRY & BIODIVERSITY,2006,3(12):1349-1355.
APA	Yang, Qing-Xiong,&Yang, Chong-Ren.(2006).Cytotoxic steroidal saponins from Polygonatum punctatum.CHEMISTRY & BIODIVERSITY,3(12),1349-1355.
MLA	Yang, Qing-Xiong,et al."Cytotoxic steroidal saponins from Polygonatum punctatum".CHEMISTRY & BIODIVERSITY 3.12(2006):1349-1355.

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