| Progress in the research of plasminogen activator inhibitor type-2 |
| Hu, JY ; Sang, YY; Zeng, Y
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| 2000-05-01
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| 发表期刊 | ACTA BIOCHIMICA ET BIOPHYSICA SINICA
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| 卷号 | 32期号:3页码:206-210 |
| 摘要 | Plasminogen activator inhibitor type-2 (PAI-2) inhibits urokinase type plasminogen activator (u-PA) most specifically and high efficiently, following the mechanism of serine proteinase inhibitor (serpin) super-family. PAI-2 plays a very important role in vivo; there are, however, two conflicting views on the role of PAI-2 in cancer. Tissue-type plasminogen activator, vitronectin, transglutaminases, fibrin and many other molecules can interact with PAI-2. Regulation factors of PAI-2 gene expression includes many regulatory elements in the promoter region, a number of agonists and conditions of organism, etc., showing that PAI-2 gene is regulated by both positive and negative mechanisms. |
| 关键词 | Pai-2
Mechanism
Function
Gene Regulation
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| 学科领域 | Biochemistry & Molecular Biology
; Biophysics
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| 收录类别 | SCI
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| 语种 | 英语
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| WOS记录号 | WOS:000087154100002
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| 引用统计 |
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| 文献类型 | 期刊论文
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| 条目标识符 | http://ir.kib.ac.cn/handle/151853/14681
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| 专题 | 植物化学与西部植物资源持续利用国家重点实验室
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| 作者单位 | Chinese Acad Sci, Kunming Inst Bot, Plant Biotechnol Dept, Kunming 650204, Peoples R China
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推荐引用方式
GB/T 7714 |
Hu, JY,Sang, YY,Zeng, Y. Progress in the research of plasminogen activator inhibitor type-2[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2000,32(3):206-210.
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| APA |
Hu, JY,Sang, YY,&Zeng, Y.(2000).Progress in the research of plasminogen activator inhibitor type-2.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,32(3),206-210.
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| MLA |
Hu, JY,et al."Progress in the research of plasminogen activator inhibitor type-2".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 32.3(2000):206-210.
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