Progress in the research of plasminogen activator inhibitor type-2
Hu, JY; Sang, YY; Zeng, Y
2000-05-01
发表期刊ACTA BIOCHIMICA ET BIOPHYSICA SINICA
卷号32期号:3页码:206-210
摘要Plasminogen activator inhibitor type-2 (PAI-2) inhibits urokinase type plasminogen activator (u-PA) most specifically and high efficiently, following the mechanism of serine proteinase inhibitor (serpin) super-family. PAI-2 plays a very important role in vivo; there are, however, two conflicting views on the role of PAI-2 in cancer. Tissue-type plasminogen activator, vitronectin, transglutaminases, fibrin and many other molecules can interact with PAI-2. Regulation factors of PAI-2 gene expression includes many regulatory elements in the promoter region, a number of agonists and conditions of organism, etc., showing that PAI-2 gene is regulated by both positive and negative mechanisms.
关键词Pai-2 Mechanism Function Gene Regulation
收录类别SCI
语种英语
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/14681
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位Chinese Acad Sci, Kunming Inst Bot, Plant Biotechnol Dept, Kunming 650204, Peoples R China
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Hu, JY,Sang, YY,Zeng, Y. Progress in the research of plasminogen activator inhibitor type-2[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2000,32(3):206-210.
APA Hu, JY,Sang, YY,&Zeng, Y.(2000).Progress in the research of plasminogen activator inhibitor type-2.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,32(3),206-210.
MLA Hu, JY,et al."Progress in the research of plasminogen activator inhibitor type-2".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 32.3(2000):206-210.
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