中国科学院昆明植物研究所机构知识库
Advanced  
KIB OpenIR  > 植物化学与西部植物资源持续利用国家重点实验室  > 期刊论文
题名: Synthesis and Antitumor Activity Evaluation of Regioselective Spiro [pyrrolidine-2,3 '-oxindole] Compounds
作者: Chen, Gang1; He, Hong-ping2; Ding, Jiang3; null(郝小江)2
刊名: HETEROCYCLIC COMMUNICATIONS
英文摘要: A series of spiro [pyrrolidine-2,3'-oxindole] derivatives were synthesized by 1,3-dipolar cycloaddition reaction of isatin, alpha-amino acid and (E)-beta-substituted-styrene. Four kinds of trapping dipolarophiles were introduced into this reaction, and the regioselectivity of these reactions proved to be the same fashion. Bioactivity screening showed these compounds were active on anti-tumor in A549 and P388 cell line, and several compounds were found to be active under the condensation of 10(-4)M.
出版日期: 2009
卷号: 15, 期号:5, 页码:355-360
语种: 英语
收录类别: SCI
学科分类: Chemistry, Organic
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/14507
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
BJ01257366.pdf(422KB)----开放获取--View Download

作者单位: 1.Xian Shiyou Univ, Coll Chem & Chem Engn, Xian 701165, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China

Recommended Citation:
Chen, G; He, HP; Ding, J; Hao, XJ.Synthesis and Antitumor Activity Evaluation of Regioselective Spiro [pyrrolidine-2,3 '-oxindole] Compounds,HETEROCYCLIC COMMUNICATIONS,2009,15(5):355-360
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Chen, Gang]'s Articles
[He, Hong-ping]'s Articles
[Ding, Jiang]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Chen, Gang]‘s Articles
[He, Hong-ping]‘s Articles
[Ding, Jiang]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: BJ01257366.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院昆明植物研究所 - Feedback
Powered by CSpace