Anti-Sports Anaemia Effects of Verbascoside and Martynoside in Mice

doi:10.1055/s-0030-1254115

	Anti-Sports Anaemia Effects of Verbascoside and Martynoside in Mice
	Zhu, M.1,2; Tan, N.1; Zhu, H.3 ; Zeng, G.1; He, W.1; Yu, B.2; Chen, X.2
	2010-08-01
发表期刊	INTERNATIONAL JOURNAL OF SPORTS MEDICINE
卷号	31 期号:8 页码:537-541
摘要	This paper aims to investigate the effects of verbascoside and martynoside isolated from Pedicularis dolichocymba on sports anaemia. Forty mice were divided into four groups: Group R (control group, nonsupplemented and maintained at rest), Group E (nonsupplemented and undergoing exercise), Group VE (supplemented with verbascoside 10 mg/kg per day and undergoing exercise), and Group ME (supplemented with martynoside 10 mg/kg per day and undergoing exercise). After 5 weeks intensive swimming exercises, we measured the RBC count, the hemoglobin concentration, the hematocrit (Hct), the mean corpuscular hemoglobin concentration (MCHC) and the mean corpuscular hemoglobin (MCH). We studied the shapes of RBC and measured the plasma malonyldialdehyde (MDA). We found Group E showed lower RBC, hemoglobin and Hct levels, higher MCHC, MCH, plasma MDA levels and the abnormally shaped RBCs percentage than Groups R, VE and ME. Group ME showed lower RBC and Hct levels, higher MCH, plasma MDA levels and the abnormally shaped RBCs percentage than Group VE. The results indicated that verbascoside and martynoside have the potential of antagonizing sports anaemia, the mechanism of this effect might be related to preventing RBC from free radical damage. Moreover, verbascoside was found to be more active than martynoside.
关键词	Verbascoside Martynoside Anti-sports Anaemia
学科领域	Sport Sciences
DOI	10.1055/s-0030-1254115
收录类别	SCI
语种	英语
WOS记录号	WOS:000280189500003
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/14503
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Zhanjiang Normal Coll, Inst Sports Sci, Zhanjiang, Peoples R China 3.Huanan Normal Univ, Inst Sports Sci, Guangzhou, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Zhu, M.,Tan, N.,Zhu, H.,et al. Anti-Sports Anaemia Effects of Verbascoside and Martynoside in Mice[J]. INTERNATIONAL JOURNAL OF SPORTS MEDICINE,2010,31(8):537-541.
APA	Zhu, M..,Tan, N..,Zhu, H..,Zeng, G..,He, W..,...&Chen, X..(2010).Anti-Sports Anaemia Effects of Verbascoside and Martynoside in Mice.INTERNATIONAL JOURNAL OF SPORTS MEDICINE,31(8),537-541.
MLA	Zhu, M.,et al."Anti-Sports Anaemia Effects of Verbascoside and Martynoside in Mice".INTERNATIONAL JOURNAL OF SPORTS MEDICINE 31.8(2010):537-541.

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