Three New 18-Oxygenated ent-Kaurane Diterpenoids from Isodon leucophyllus
Zhang, Hai Bo1,2; Pu, Jian Xin1; Zhao, Yong1; He, Fei1; Zhao, Wei1; Lou, Li Guang3; Xiao, Wei Lie1; Sun, Han Dong1
2010-12-01
发表期刊NATURAL PRODUCT COMMUNICATIONS
ISSN1934-578X
卷号5期号:12页码:1873-1876
摘要Three new 18-oxygenated ent-kaurane diterpenoids, isoleuconins A-C (1-3) and ten known diterpenoids were isolated from the aerial parts of Isodon leucophyllus. The structures were elucidated by 1D and 2D NMR spectroscopic analysis. All of the compounds were evaluated for their cytotoxicity. Rabdokunmin A (13) showed significant cytotoxicity against HT-29 cells, with an IC(50) value of 6.2 mu M.
关键词Isodon Leucophyllus Labiatae Ent-kaurane Diterpenoid Cytotoxicity
资助信息NSFC [30772637, 30830119]; NSFC-Joint Foundation of Yunnan Province [U0832602]; Major State Basic Research Development Program of China [2009CB522300, 2009CB940900]; Natural Science Foundation of Yunnan Province [2008CD162]; Science and Technology Program of Yunnan Province [2008IF010]
收录类别SCI
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/14483
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China
3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
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Zhang, Hai Bo,Pu, Jian Xin,Zhao, Yong,et al. Three New 18-Oxygenated ent-Kaurane Diterpenoids from Isodon leucophyllus[J]. NATURAL PRODUCT COMMUNICATIONS,2010,5(12):1873-1876.
APA Zhang, Hai Bo.,Pu, Jian Xin.,Zhao, Yong.,He, Fei.,Zhao, Wei.,...&Sun, Han Dong.(2010).Three New 18-Oxygenated ent-Kaurane Diterpenoids from Isodon leucophyllus.NATURAL PRODUCT COMMUNICATIONS,5(12),1873-1876.
MLA Zhang, Hai Bo,et al."Three New 18-Oxygenated ent-Kaurane Diterpenoids from Isodon leucophyllus".NATURAL PRODUCT COMMUNICATIONS 5.12(2010):1873-1876.
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