Phenolic constituents from Rhopalocnemis phalloides with DPPH radical scavenging activity
She, Gai-Mei1,2; Hu, Jin-Bo1; Zhang, Ying-Jun1; Yang, Chong-Ren1
2010
发表期刊PHARMACEUTICAL BIOLOGY
卷号48期号:1页码:116-119
摘要The 80% aqueous acetone extract of the whole plant of Rhopalocnemis phalloides Jungh. (Balanophoraceae) showed obvious radical scavenging activity (SC(50) = 32.1 mu g/mL) on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical assay. Further chemical investigation of the extract led to the isolation of 12 phenolic compounds (1-12). Among these, bis-6,8'-catechinylmethane (2), a flavan-3-ol dimer, was first isolated as a natural product from Rhopalocnemis phalloides. The full NMR assignments of bis-catechinylmethanes (1 and 2) are reported for the first time, on the basis of detailed spectroscopic analysis. The DPPH assay showed that flavan-3-ol dimers (1-3) had remarkable free radical scavenging activity, while flavonoid aglycones (4 and 9) presented stronger activities than those of their glycosides (5-8 and 10).
关键词Balanophoraceae Rhopalocnemis Phalloides Flavan-3-ol Dimer Dpph Radical
学科领域Plant Sciences ; Medical Laboratory Technology ; Pharmacology & Pharmacy
DOI10.3109/13880200903032757
收录类别SCI
语种英语
WOS研究方向Plant Sciences ; Medical Laboratory Technology ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Medical Laboratory Technology ; Pharmacology & Pharmacy
WOS记录号WOS:000273992300018
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被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/14473
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Beijing Univ Chinese Med, Sch Chinese Pharm, Beijing, Peoples R China
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She, Gai-Mei,Hu, Jin-Bo,Zhang, Ying-Jun,et al. Phenolic constituents from Rhopalocnemis phalloides with DPPH radical scavenging activity[J]. PHARMACEUTICAL BIOLOGY,2010,48(1):116-119.
APA She, Gai-Mei,Hu, Jin-Bo,Zhang, Ying-Jun,&Yang, Chong-Ren.(2010).Phenolic constituents from Rhopalocnemis phalloides with DPPH radical scavenging activity.PHARMACEUTICAL BIOLOGY,48(1),116-119.
MLA She, Gai-Mei,et al."Phenolic constituents from Rhopalocnemis phalloides with DPPH radical scavenging activity".PHARMACEUTICAL BIOLOGY 48.1(2010):116-119.
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