| Chemical Constituents of Dracocephalum forrestii | |
Li, Su-Mei1,3; Yang, Xian-Wen2,3; Li, Yong-Li2; Shen, Yun-Heng2; Feng, Lin2; Wang, Yue-Hu1 ; Zeng, Hua-Wu2; Liu, Xiao-Hua2; Zhang, Chang-Sheng3; Long, Chun-Lin1; Zhang, Wei-Dong2
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| 通讯作者 | long@mail.kib.ac.cn ; wdzhangy@hotmail.com |
| 2009-12-01 | |
| 发表期刊 | PLANTA MEDICA
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| ISSN | 0032-0943 |
| 卷号 | 75期号:15页码:1591-1596 |
| 摘要 | A systematic phytochemical examination of the whole plant Dracocephalum forrestii led to the isolation of 4 new and 65 known chemical constituents. By detailed 1D and 2D NMR spectroscopic analyses, the new compounds were identified as 4-hydroxy-3-methoxyphenylethanol 8-O-[(6-O-syringoyl)-beta-D-glucopyranoside] (1), 3,4,5-trimethoxyphenylethanol beta-D-glucopyranoside (2), 4-O-[beta-D-glucopyranosyl-(1 -> 3)-alpha-L-rhamnopyranosyl]phenylethylcinnamamide (3), and 9 ''-O-n-butyl lithospermate (4). The new isolates were evaluated for inhibitory activities against LPS-induced NO production in RAW 264.7 macrophages. Compound 2 revealed a moderate effect without any cytotoxicity under the assayed concentrations. |
| 关键词 | Dracocephalum Forrestii Lamiaceae Phenylethanoids Lignans Raw 264.7 Macrophages No |
| 学科领域 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| DOI | 10.1055/s-0029-1185868 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000273178400007 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/14071 |
| 专题 | 资源植物与生物技术所级重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Second Mil Med Univ, Dept Nat Prod Chem, Sch Pharm, Shanghai 200433, Peoples R China 3.Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, S China Sea Inst Oceanol, Guangzhou, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Su-Mei,Yang, Xian-Wen,Li, Yong-Li,et al. Chemical Constituents of Dracocephalum forrestii[J]. PLANTA MEDICA,2009,75(15):1591-1596. |
| APA | Li, Su-Mei.,Yang, Xian-Wen.,Li, Yong-Li.,Shen, Yun-Heng.,Feng, Lin.,...&Zhang, Wei-Dong.(2009).Chemical Constituents of Dracocephalum forrestii.PLANTA MEDICA,75(15),1591-1596. |
| MLA | Li, Su-Mei,et al."Chemical Constituents of Dracocephalum forrestii".PLANTA MEDICA 75.15(2009):1591-1596. |
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