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题名: Chemical Constituents of Dracocephalum forrestii
作者: Li, Su-Mei1, 3; Yang, Xian-Wen2, 3; Li, Yong-Li2; Shen, Yun-Heng2; Feng, Lin2; Wang, Yue-Hu1; Zeng, Hua-Wu2; Liu, Xiao-Hua2; Zhang, Chang-Sheng3; Long, Chun-Lin1; Zhang, Wei-Dong2
刊名: PLANTA MEDICA
关键词: Dracocephalum forrestii ; Lamiaceae ; phenylethanoids ; lignans ; RAW 264.7 macrophages ; NO
英文摘要: A systematic phytochemical examination of the whole plant Dracocephalum forrestii led to the isolation of 4 new and 65 known chemical constituents. By detailed 1D and 2D NMR spectroscopic analyses, the new compounds were identified as 4-hydroxy-3-methoxyphenylethanol 8-O-[(6-O-syringoyl)-beta-D-glucopyranoside] (1), 3,4,5-trimethoxyphenylethanol beta-D-glucopyranoside (2), 4-O-[beta-D-glucopyranosyl-(1 -> 3)-alpha-L-rhamnopyranosyl]phenylethylcinnamamide (3), and 9 ''-O-n-butyl lithospermate (4). The new isolates were evaluated for inhibitory activities against LPS-induced NO production in RAW 264.7 macrophages. Compound 2 revealed a moderate effect without any cytotoxicity under the assayed concentrations.
出版日期: 2009-12-01
卷号: 75, 期号:15, 页码:1591-1596
语种: 英语
收录类别: SCI
学科分类: Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy
ISSN号: 0032-0943
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/14071
Appears in Collections:资源植物与生物技术所级重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Second Mil Med Univ, Dept Nat Prod Chem, Sch Pharm, Shanghai 200433, Peoples R China
3.Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, S China Sea Inst Oceanol, Guangzhou, Guangdong, Peoples R China

Recommended Citation:
Li, SM; Yang, XW; Li, YL; Shen, YH; Feng, L; Wang, YH; Zeng, HW; Liu, XH; Zhang, CS; Long, CL; Zhang, WD.Chemical Constituents of Dracocephalum forrestii,PLANTA MEDICA,2009,75(15):1591-1596
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