Chemical Constituents of Dracocephalum forrestii
Li, Su-Mei1,3; Yang, Xian-Wen2,3; Li, Yong-Li2; Shen, Yun-Heng2; Feng, Lin2; Wang, Yue-Hu1; Zeng, Hua-Wu2; Liu, Xiao-Hua2; Zhang, Chang-Sheng3; Long, Chun-Lin1; Zhang, Wei-Dong2
2009-12-01
发表期刊PLANTA MEDICA
ISSN0032-0943
卷号75期号:15页码:1591-1596
摘要A systematic phytochemical examination of the whole plant Dracocephalum forrestii led to the isolation of 4 new and 65 known chemical constituents. By detailed 1D and 2D NMR spectroscopic analyses, the new compounds were identified as 4-hydroxy-3-methoxyphenylethanol 8-O-[(6-O-syringoyl)-beta-D-glucopyranoside] (1), 3,4,5-trimethoxyphenylethanol beta-D-glucopyranoside (2), 4-O-[beta-D-glucopyranosyl-(1 -> 3)-alpha-L-rhamnopyranosyl]phenylethylcinnamamide (3), and 9 ''-O-n-butyl lithospermate (4). The new isolates were evaluated for inhibitory activities against LPS-induced NO production in RAW 264.7 macrophages. Compound 2 revealed a moderate effect without any cytotoxicity under the assayed concentrations.
关键词Dracocephalum Forrestii Lamiaceae Phenylethanoids Lignans Raw 264.7 Macrophages No
资助信息The authors wish to thank Professor Li-shang Xie in Kunming Institute of Botany, Chinese Academy of Sciences for identification of the plant. This research was Supported by Changjiang Scholars and Innovative Research Team in University (PCSIRT), NCET Foundation, NSFC (30725045), National 863 Program (2006AA02Z338), Shanghai Leading Academic Discipline Project (13906), and in part by the Ministry of Science and Technology of China (Nos. 2004DKA30430, 2005DKA21 006) and the Ministry of Education of China through its III Project (B08044, CUN 985-3-3).
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1055/s-0029-1185868
收录类别SCI
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000273178400007
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/14071
专题资源植物与生物技术所级重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Second Mil Med Univ, Dept Nat Prod Chem, Sch Pharm, Shanghai 200433, Peoples R China
3.Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, S China Sea Inst Oceanol, Guangzhou, Guangdong, Peoples R China
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Li, Su-Mei,Yang, Xian-Wen,Li, Yong-Li,et al. Chemical Constituents of Dracocephalum forrestii[J]. PLANTA MEDICA,2009,75(15):1591-1596.
APA Li, Su-Mei.,Yang, Xian-Wen.,Li, Yong-Li.,Shen, Yun-Heng.,Feng, Lin.,...&Zhang, Wei-Dong.(2009).Chemical Constituents of Dracocephalum forrestii.PLANTA MEDICA,75(15),1591-1596.
MLA Li, Su-Mei,et al."Chemical Constituents of Dracocephalum forrestii".PLANTA MEDICA 75.15(2009):1591-1596.
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