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Chemical Constituents of Dracocephalum forrestii
Li, Su-Mei1,3; Yang, Xian-Wen2,3; Li, Yong-Li2; Shen, Yun-Heng2; Feng, Lin2; Wang, Yue-Hu1; Zeng, Hua-Wu2; Liu, Xiao-Hua2; Zhang, Chang-Sheng3; Long, Chun-Lin1; Zhang, Wei-Dong2
Corresponding ;
Source PublicationPLANTA MEDICA
AbstractA systematic phytochemical examination of the whole plant Dracocephalum forrestii led to the isolation of 4 new and 65 known chemical constituents. By detailed 1D and 2D NMR spectroscopic analyses, the new compounds were identified as 4-hydroxy-3-methoxyphenylethanol 8-O-[(6-O-syringoyl)-beta-D-glucopyranoside] (1), 3,4,5-trimethoxyphenylethanol beta-D-glucopyranoside (2), 4-O-[beta-D-glucopyranosyl-(1 -> 3)-alpha-L-rhamnopyranosyl]phenylethylcinnamamide (3), and 9 ''-O-n-butyl lithospermate (4). The new isolates were evaluated for inhibitory activities against LPS-induced NO production in RAW 264.7 macrophages. Compound 2 revealed a moderate effect without any cytotoxicity under the assayed concentrations.
KeywordDracocephalum Forrestii Lamiaceae Phenylethanoids Lignans Raw 264.7 Macrophages No
Subject AreaPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
Indexed BySCI
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000273178400007
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Cited Times:9[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Second Mil Med Univ, Dept Nat Prod Chem, Sch Pharm, Shanghai 200433, Peoples R China
3.Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, S China Sea Inst Oceanol, Guangzhou, Guangdong, Peoples R China
Recommended Citation
GB/T 7714
Li, Su-Mei,Yang, Xian-Wen,Li, Yong-Li,et al. Chemical Constituents of Dracocephalum forrestii[J]. PLANTA MEDICA,2009,75(15):1591-1596.
APA Li, Su-Mei.,Yang, Xian-Wen.,Li, Yong-Li.,Shen, Yun-Heng.,Feng, Lin.,...&Zhang, Wei-Dong.(2009).Chemical Constituents of Dracocephalum forrestii.PLANTA MEDICA,75(15),1591-1596.
MLA Li, Su-Mei,et al."Chemical Constituents of Dracocephalum forrestii".PLANTA MEDICA 75.15(2009):1591-1596.
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