Four compounds were isolated from dry seeds of Cipadessa baccifera (Roth) Mig. along with the known 2 beta ,3 beta ,4 beta -trihydroxypregnan-16-one, febrifugin, and khaysin T. Their structures were elucidated on the basis of spectral analysis to be cipadesin, 17 alpha ,20R-dihydroxypregnan-3,16-dione, 1,4-epoxy-16-hydroxyheneicos-1,3,12,14,18-pentaene and 1,4-epoxy-16-hydroxyheneicos-1,3,12,14-tetraene. (C) 2000 Elsevier Science Ltd. All rights reserved.