Chemical constituents of two Chinese Magnoliaceae plants, Tsoongiodendron odorum and Manglietiastrum sinicum, and their inhibition of platelet aggregation
Wang, BG; Hong, X; Li, L; Zhou, J; Hao, XJ
2000-08-01
发表期刊PLANTA MEDICA
卷号66期号:6页码:511-515
摘要Phytochemical investigations of Tsoongiodendron odorum and Manglietiastrum sinicum, both Magnoliaceae, led to the isolation of twenty compounds in total. Among them, one was a new sesquiterpene, 11-O-oleoyl-beta-eudesmol (2), and another, 1-(3,4-dimethoxypheny)-4-(3,4-methylenedioxyphenyl)- 2,3-dimethylbutane (12) was isolated as a natural product for the first time. Moreover, C-13-NMR spectral data of isoguaiacin (16) are reported here for the first time. Structure elucidations for compounds reported here were mainly based on their spectral data. The ethanolic extracts of T. odorum and M. sinicum, and six pure compounds, 4(15)-eudesmen-11-ol (beta-eudesmol) (1), 1 beta-hydroxy-4(15),11(13)-eudesmadien-12,6 alpha-olide (reynosin) (3), 3,11 (13)-eudesmadien-12,6 alpha-olide (alpha-cyclocostunolide) (5), erythro-1-(4-hydroxy-3-methoxyphenyl)-4-(3,4-methylene-dioxyphenyl)-2,3-dimethylbutane (11), nectandrin-B (18), and syringaresinol (19), displayed considerable inhibition against platelet aggregation induced by AA, by ADP, or by PAF.
关键词Tsoongiodendron Odorum Manglietiastrum Sinicum Magnoliaceae Chemical Constituents Inhibition Platelet Aggregation
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
收录类别SCI
语种英语
WOS记录号WOS:000088966100003
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/13637
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位Chinese Acad Sci, Kunming Inst Bot, Lab Phytochem, Kunming 650204, Peoples R China
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Wang, BG,Hong, X,Li, L,et al. Chemical constituents of two Chinese Magnoliaceae plants, Tsoongiodendron odorum and Manglietiastrum sinicum, and their inhibition of platelet aggregation[J]. PLANTA MEDICA,2000,66(6):511-515.
APA Wang, BG,Hong, X,Li, L,Zhou, J,&Hao, XJ.(2000).Chemical constituents of two Chinese Magnoliaceae plants, Tsoongiodendron odorum and Manglietiastrum sinicum, and their inhibition of platelet aggregation.PLANTA MEDICA,66(6),511-515.
MLA Wang, BG,et al."Chemical constituents of two Chinese Magnoliaceae plants, Tsoongiodendron odorum and Manglietiastrum sinicum, and their inhibition of platelet aggregation".PLANTA MEDICA 66.6(2000):511-515.
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