Two new coumarin derivatives from the roots of Heradeum rapula

doi:10.1055/s-2004-827164

	Two new coumarin derivatives from the roots of Heradeum rapula
	Niu, XM ; Li, SH; Wu, LX ; Li, L; Gao, LH ; Sun, HD
	2004-06-01
发表期刊	PLANTA MEDICA
ISSN	0032-0943
卷号	70 期号:6 页码:578-581
摘要	Two new coumarins, 13-O-[beta-D-apiofuranosyl(1-->6)-beta-D-glucopyranosyl]-(12R)-heraclenol (1) and (12R,12"R)-diheraclenol (2) were isolated from the acetone extract of the fresh roots of Heracleum rapula. Their structures were determined by means of spectroscopic analysis and, in the case of compound 1, the structure elucidation was supported by acid hydrolysis. Compound 1 is a coumarin glycoside while 2 is a coumarin dimer. The inhibitory effects of 1, its aglycone (3), and 2 on rabbit platelet aggregation induced by PAF, AA and ADP were tested. Weak activities were observed for each compound with the percentages of inhibition in the range of 0.7-24.8%.
学科领域	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI	10.1055/s-2004-827164
收录类别	SCI
语种	英语
WOS记录号	WOS:000222406500020
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/13615
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Guiyang Med Coll, Guiyang, Guizhou, Peoples R China 3.Kunming Med Coll, Yunnan Pharmacol Lab Nat Prod, Kunming, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Niu, XM,Li, SH,Wu, LX,et al. Two new coumarin derivatives from the roots of Heradeum rapula[J]. PLANTA MEDICA,2004,70(6):578-581.
APA	Niu, XM,Li, SH,Wu, LX,Li, L,Gao, LH,&Sun, HD.(2004).Two new coumarin derivatives from the roots of Heradeum rapula.PLANTA MEDICA,70(6),578-581.
MLA	Niu, XM,et al."Two new coumarin derivatives from the roots of Heradeum rapula".PLANTA MEDICA 70.6(2004):578-581.

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