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题名: Two new coumarin derivatives from the roots of Heradeum rapula
作者: Niu, XM; null(黎胜红); Wu, LX; Li, L; Gao, LH; null(孙汉董)
刊名: PLANTA MEDICA
英文摘要: Two new coumarins, 13-O-[beta-D-apiofuranosyl(1-->6)-beta-D-glucopyranosyl]-(12R)-heraclenol (1) and (12R,12"R)-diheraclenol (2) were isolated from the acetone extract of the fresh roots of Heracleum rapula. Their structures were determined by means of spectroscopic analysis and, in the case of compound 1, the structure elucidation was supported by acid hydrolysis. Compound 1 is a coumarin glycoside while 2 is a coumarin dimer. The inhibitory effects of 1, its aglycone (3), and 2 on rabbit platelet aggregation induced by PAF, AA and ADP were tested. Weak activities were observed for each compound with the percentages of inhibition in the range of 0.7-24.8%.
出版日期: 2004-06-01
卷号: 70, 期号:6, 页码:578-581
DOI标识: 10.1055/s-2004-827164
语种: 英语
ISSN号: 0032-0943
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/13615
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Guiyang Med Coll, Guiyang, Guizhou, Peoples R China
3.Kunming Med Coll, Yunnan Pharmacol Lab Nat Prod, Kunming, Yunnan, Peoples R China

Recommended Citation:
Niu, XM; Li, SH; Wu, LX; Li, L; Gao, LH; Sun, HD.Two new coumarin derivatives from the roots of Heradeum rapula,PLANTA MEDICA,2004,70(6):578-581
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