Two new coumarin derivatives from the roots of Heradeum rapula
Niu, XM; Li, SH; Wu, LX; Li, L; Gao, LH; Sun, HD
2004-06-01
发表期刊PLANTA MEDICA
ISSN0032-0943
卷号70期号:6页码:578-581
摘要Two new coumarins, 13-O-[beta-D-apiofuranosyl(1-->6)-beta-D-glucopyranosyl]-(12R)-heraclenol (1) and (12R,12"R)-diheraclenol (2) were isolated from the acetone extract of the fresh roots of Heracleum rapula. Their structures were determined by means of spectroscopic analysis and, in the case of compound 1, the structure elucidation was supported by acid hydrolysis. Compound 1 is a coumarin glycoside while 2 is a coumarin dimer. The inhibitory effects of 1, its aglycone (3), and 2 on rabbit platelet aggregation induced by PAF, AA and ADP were tested. Weak activities were observed for each compound with the percentages of inhibition in the range of 0.7-24.8%.
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1055/s-2004-827164
收录类别SCI
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000222406500020
引用统计
被引频次:14[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/13615
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Guiyang Med Coll, Guiyang, Guizhou, Peoples R China
3.Kunming Med Coll, Yunnan Pharmacol Lab Nat Prod, Kunming, Yunnan, Peoples R China
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GB/T 7714
Niu, XM,Li, SH,Wu, LX,et al. Two new coumarin derivatives from the roots of Heradeum rapula[J]. PLANTA MEDICA,2004,70(6):578-581.
APA Niu, XM,Li, SH,Wu, LX,Li, L,Gao, LH,&Sun, HD.(2004).Two new coumarin derivatives from the roots of Heradeum rapula.PLANTA MEDICA,70(6),578-581.
MLA Niu, XM,et al."Two new coumarin derivatives from the roots of Heradeum rapula".PLANTA MEDICA 70.6(2004):578-581.
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