Two New Phenylpropanoid Derivatives and Other Constituents from Illicium simonsii Active Against Oral Microbial Organisms
Liu, Ji-Feng1,2; Jiang, Zhi-Yong1; Geng, Chang-An1,2; Zou, Xiao-Bin3; Shi, Yao3; Ma, Yun-Bao1; Zhang, Xue-Mei1; Chen, Ji-Jun1
2010-09-01
Source PublicationPLANTA MEDICA
ISSN0032-0943
Volume76Issue:13Pages:1464-1467
AbstractBioassay-guided fractionation of the ethanol extract of the leaves and stems of Illicium simonsii led to the isolation of two new compounds, simonin A (1) and 1-hydroxyl-2-O-beta-D-6'-acetyl-glucopyranosyl-4-allylbenzene (2), along with eight known compounds. Their structures were elucidated by spectroscopic analysis. The isolates were tested for anti-oral microbial activity using a microdilution method. Compounds 1 and 3-6 showed significant activities against oral microbial organisms (Actinomyces viscosus, Streptococcus mutans, Streptococcus sanguis, and Actinomyces naeslundii), with minimum inhibitory concentration (MIC) values ranging from 1.95 to 31.25 mu g/mL in vitro.
KeywordIlliciaceae Illicium Simonsii Neolignans Anti-oral Microbial Activity
Subject AreaPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1055/s-0029-1240939
Indexed BySCI
Language英语
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000281742700013
Citation statistics
Cited Times:7[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/13589
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
3.Hawley & Hazel Chem ZS Co Ltd, Zhongshan, Guangdong, Peoples R China
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GB/T 7714
Liu, Ji-Feng,Jiang, Zhi-Yong,Geng, Chang-An,et al. Two New Phenylpropanoid Derivatives and Other Constituents from Illicium simonsii Active Against Oral Microbial Organisms[J]. PLANTA MEDICA,2010,76(13):1464-1467.
APA Liu, Ji-Feng.,Jiang, Zhi-Yong.,Geng, Chang-An.,Zou, Xiao-Bin.,Shi, Yao.,...&Chen, Ji-Jun.(2010).Two New Phenylpropanoid Derivatives and Other Constituents from Illicium simonsii Active Against Oral Microbial Organisms.PLANTA MEDICA,76(13),1464-1467.
MLA Liu, Ji-Feng,et al."Two New Phenylpropanoid Derivatives and Other Constituents from Illicium simonsii Active Against Oral Microbial Organisms".PLANTA MEDICA 76.13(2010):1464-1467.
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