Cytotoxic Activity of Trijugin-Type Limonoids from Cipadessa baccifera | |
Ning, Jing1,2; Di, Ying-Tong1; Wang, Yuan-Yuan1; He, Hong-Ping1; Fang, Xin1; Li, Yan1; Li, Shun-Lin1; Hao, Xiao-Jiang1 | |
2010-11-01 | |
发表期刊 | PLANTA MEDICA |
ISSN | 0032-0943 |
卷号 | 76期号:16页码:1907-1910 |
摘要 | Two new trijugin-type limonoids, cipatrijugins E and F (1 and 2), together with the known cipatrijugins A and D (3-4), were isolated from the stem bark of Cipadessa baccifera. All structures were elucidated by spectroscopic analysis. The in vitro cytotoxicity of compounds 1-4 was also tested. Compound 1 showed significant in vitro cytotoxicity against MCF-7, SW480, HL-60, and SMMC-7721 cells, with IC(50) values of 5.0, 6.6, 4.5, and 21.6 mu M, respectively. |
关键词 | Cipadessa Baccifera Meliaceae Trijugin-type Limonoids Cytotoxicity |
学科领域 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
DOI | 10.1055/s-0030-1249979 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000284144400024 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/13583 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Ning, Jing,Di, Ying-Tong,Wang, Yuan-Yuan,et al. Cytotoxic Activity of Trijugin-Type Limonoids from Cipadessa baccifera[J]. PLANTA MEDICA,2010,76(16):1907-1910. |
APA | Ning, Jing.,Di, Ying-Tong.,Wang, Yuan-Yuan.,He, Hong-Ping.,Fang, Xin.,...&Hao, Xiao-Jiang.(2010).Cytotoxic Activity of Trijugin-Type Limonoids from Cipadessa baccifera.PLANTA MEDICA,76(16),1907-1910. |
MLA | Ning, Jing,et al."Cytotoxic Activity of Trijugin-Type Limonoids from Cipadessa baccifera".PLANTA MEDICA 76.16(2010):1907-1910. |
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