Cytotoxic Activity of Trijugin-Type Limonoids from Cipadessa baccifera
Ning, Jing1,2; Di, Ying-Tong1; Wang, Yuan-Yuan1; He, Hong-Ping1; Fang, Xin1; Li, Yan1; Li, Shun-Lin1; Hao, Xiao-Jiang1
2010-11-01
发表期刊PLANTA MEDICA
ISSN0032-0943
卷号76期号:16页码:1907-1910
摘要Two new trijugin-type limonoids, cipatrijugins E and F (1 and 2), together with the known cipatrijugins A and D (3-4), were isolated from the stem bark of Cipadessa baccifera. All structures were elucidated by spectroscopic analysis. The in vitro cytotoxicity of compounds 1-4 was also tested. Compound 1 showed significant in vitro cytotoxicity against MCF-7, SW480, HL-60, and SMMC-7721 cells, with IC(50) values of 5.0, 6.6, 4.5, and 21.6 mu M, respectively.
关键词Cipadessa Baccifera Meliaceae Trijugin-type Limonoids Cytotoxicity
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1055/s-0030-1249979
收录类别SCI
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000284144400024
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/13583
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
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Ning, Jing,Di, Ying-Tong,Wang, Yuan-Yuan,et al. Cytotoxic Activity of Trijugin-Type Limonoids from Cipadessa baccifera[J]. PLANTA MEDICA,2010,76(16):1907-1910.
APA Ning, Jing.,Di, Ying-Tong.,Wang, Yuan-Yuan.,He, Hong-Ping.,Fang, Xin.,...&Hao, Xiao-Jiang.(2010).Cytotoxic Activity of Trijugin-Type Limonoids from Cipadessa baccifera.PLANTA MEDICA,76(16),1907-1910.
MLA Ning, Jing,et al."Cytotoxic Activity of Trijugin-Type Limonoids from Cipadessa baccifera".PLANTA MEDICA 76.16(2010):1907-1910.
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