| Neoclerodane Diterpenoids from Scutellaria barbata | |
Zhu, Feng1,2; Di, Ying-Tong1 ; Li, Xing-Yao1; Liu, Ling-Li1; Zhang, Qiang1; Li, Yan1; Hao, Xiao-Jiang1; He, Hong-Ping1
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| 通讯作者 | He, HP (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, 132 Lanhei Rd, Kunming 650204, Yunnan, Peoples R China |
| 2011-09-01 | |
| 发表期刊 | PLANTA MEDICA
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| ISSN | 0032-0943 |
| 卷号 | 77期号:13页码:1536-1541 |
| 摘要 | Eight new neoclerodane diterpenoids (1-8), scutebatas H-O, together with eight known compounds, have been isolated from the whole plant of Scutellaria barbata D. Don. Their structures were elucidated on the basis of spectroscopic studies. In vitro cytotoxicity of selected compounds against cancer cell lines HL-60, SMMC-7721, A-549, MCF-7, and SW480 was evaluated. Compounds 5, 6, 7 showed moderate cytotoxicities against several human cancer cell lines, with IC(50) values ranging from 12.6-31.4 mu M. In addition, compound 1 showed selective cytotoxicity against MCF-7. |
| 关键词 | Scutellaria Barbata Lamiaceae Neoclerodane Diterpenoids Scutebatas H-o Cytotoxicity |
| 学科领域 | Plant Sciences ; Pharmacology & Pharmacy |
| DOI | 10.1055/s-0030-1270797 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000294481300013 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/13577 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Feng,Di, Ying-Tong,Li, Xing-Yao,et al. Neoclerodane Diterpenoids from Scutellaria barbata[J]. PLANTA MEDICA,2011,77(13):1536-1541. |
| APA | Zhu, Feng.,Di, Ying-Tong.,Li, Xing-Yao.,Liu, Ling-Li.,Zhang, Qiang.,...&He, Hong-Ping.(2011).Neoclerodane Diterpenoids from Scutellaria barbata.PLANTA MEDICA,77(13),1536-1541. |
| MLA | Zhu, Feng,et al."Neoclerodane Diterpenoids from Scutellaria barbata".PLANTA MEDICA 77.13(2011):1536-1541. |
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