| Antimicrobial, Cytotoxic Lignans and Terpenoids from the Twigs of Pseudolarix kaempferi | |
| He, Wen-Jun1,2; Chu, Hong-Biao1; Zhang, Yu-Mei1; Han, Hong-Jin1; Yan, He1,2; Zeng, Guang-Zhi1; Fu, Zhao-Hui1; Olubanke, Ogunlana3; Tan, Ning-Hua1 | |
| 通讯作者 | Tan, NH (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China |
| 2011-11-01 | |
| 发表期刊 | PLANTA MEDICA
 |
| ISSN | 0032-0943 |
| 卷号 | 77期号:17页码:1924-1931 |
| 摘要 | Seven new compounds, including four lignans, (+)-(8S, 8'S)-9,9'-dibenzoylsecoisolariciresinol (1), (+)-(8S*, 8'R*)-4,4'-dimethyloxomatairesinol (2), (+)-(7S*, 8R*, 8'R*, 9'S*)-9'-n-butoxytsugacetal (3), and pseudolarkaemin A (4), a pyronane glycoside, pseudolarkaemin B (5), an ent-beyerene glycoside, pseudolarkaemin C (6), and a triterpene, 25-epi-pseudolarolide Q (7), along with 25 known compounds (8-32) were isolated from the twigs of Pseudolarix kaempferi. Their structures were elucidated mainly by the analysis of their NMR and MS data. Pseudolarolide C acid (24) was isolated for the first time as a natural product. All compounds were evaluated for antimicrobial activity against Candida albicans and Staphylococcus aureus, and cytotoxic activity against K562, HT29, B16, BGC-823, BEL-7402, SGC-7901, U251, and A549 cancer cell lines were assayed. Results indicated that the new compounds 3, 7, and some known compounds showed antimicrobial and cytotoxic activities. |
| 关键词 | Pseudolarix Kaempferi Pinaceae Lignans Terpenoids Antimicrobial Cytotoxic |
| 学科领域 | Plant Sciences ; Pharmacology & Pharmacy |
| DOI | 10.1055/s-0031-1280020 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000298851200010 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/13567 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China 3.Covenant Univ, Dept Biol Sci, Coll Sci & Technol, Ota, Ogun State, Nigeria |
| 推荐引用方式 GB/T 7714 | He, Wen-Jun,Chu, Hong-Biao,Zhang, Yu-Mei,et al. Antimicrobial, Cytotoxic Lignans and Terpenoids from the Twigs of Pseudolarix kaempferi[J]. PLANTA MEDICA,2011,77(17):1924-1931. |
| APA | He, Wen-Jun.,Chu, Hong-Biao.,Zhang, Yu-Mei.,Han, Hong-Jin.,Yan, He.,...&Tan, Ning-Hua.(2011).Antimicrobial, Cytotoxic Lignans and Terpenoids from the Twigs of Pseudolarix kaempferi.PLANTA MEDICA,77(17),1924-1931. |
| MLA | He, Wen-Jun,et al."Antimicrobial, Cytotoxic Lignans and Terpenoids from the Twigs of Pseudolarix kaempferi".PLANTA MEDICA 77.17(2011):1924-1931. |
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