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题名: Phenolic Compounds from the Branches of Eucalyptus maideni
作者: Tian, Li-Wen1, 2; Xu, Min1; null(李艳)1; Li, Xing-Yao1, 2; Wang, Dong1; Zhu, Hong-Tao1; Yang, Chong-Ren1, 3; null(张颖君)1
刊名: CHEMISTRY & BIODIVERSITY
关键词: Eucalyptus maideni ; Cytotoxic activity ; Phenolic compounds ; Eucalmaidin F
英文摘要: Three new phenolic compounds, eucalmaidin F (1), (3S)-5-guaiacyl-3-hydroxypentanoic acid (2), and 8-beta-C-glucopyranosyl-5,7-dihydroxy-2-isobutylchromone (3), were isolated from the branches of E. maideni, together with 30 known compounds, including four phenylpropanoids, three lignans, four phloroglucinol glucosides, five dihydroflavonoids, seven simple phenolic compounds, six terpenoids, and glycerol. The new structures were established by spectroscopic studies (MS, and 1D- and 2D-NMR), chemical degradation, and modified Mosher's method. Compounds 3, guaiacylglycerol, 3-hydroxy-1-(4-hydroxyphenyl)propan-1-one, caffeic acid, (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid, (7'S,8R,8'R)-lyoniresinol, (+)-lyoresinol 3a-O-a-L-rhamnopyranoside, garcimangosone, phlorocetophenone 2'-glucopyranoside, (+)-taxifolin 3a-O-a-L-rhamnopyranoside, (+)-aromadendrin, (+)-taxifolin, resveratrol, piceatannol, 3,4,5-trihydroxyphenol. Tachiaside, gallic acid, macrocapals A und G, and oleuropeic acid were evaluated for their cytotoxicities against five human cancer cell lines. Resveratrol, piceatannol, gallic acid, and macrocapal G exhibited moderate inhibitory effects on human myeloid heukemia HL-60 cell, with IC50 values of 22.05, 22.05, 7.75, and 31.93 mu M, respectively; and only macrocapal G showed inhibitory effect on hepatocellular carcinoma SMMC-7721 cell, with an IC50 value of 26.75 mu M.
出版日期: 2012
卷号: 9, 期号:1, 页码:123-130
语种: 英语
收录类别: SCI
学科分类: Biochemistry & Molecular Biology; Chemistry, Multidisciplinary
ISSN号: 1612-1872
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/10431
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W Chin, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Weihe Biotech Res & Dev Ctr, Yuxi 653101, Peoples R China

Recommended Citation:
Tian, LW; Xu, M; Li, Y; Li, XY; Wang, D; Zhu, HT; Yang, CR; Zhang, YJ.Phenolic Compounds from the Branches of Eucalyptus maideni,CHEMISTRY & BIODIVERSITY,2012,9(1):123-130
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