Phenolic Compounds from the Branches of Eucalyptus maideni
Tian, Li-Wen1,2; Xu, Min1; Li, Yan1; Li, Xing-Yao1,2; Wang, Dong1; Zhu, Hong-Tao1; Yang, Chong-Ren1,3; Zhang, Ying-Jun1
2012
发表期刊CHEMISTRY & BIODIVERSITY
ISSN1612-1872
卷号9期号:1页码:123-130
摘要Three new phenolic compounds, eucalmaidin F (1), (3S)-5-guaiacyl-3-hydroxypentanoic acid (2), and 8-beta-C-glucopyranosyl-5,7-dihydroxy-2-isobutylchromone (3), were isolated from the branches of E. maideni, together with 30 known compounds, including four phenylpropanoids, three lignans, four phloroglucinol glucosides, five dihydroflavonoids, seven simple phenolic compounds, six terpenoids, and glycerol. The new structures were established by spectroscopic studies (MS, and 1D- and 2D-NMR), chemical degradation, and modified Mosher's method. Compounds 3, guaiacylglycerol, 3-hydroxy-1-(4-hydroxyphenyl)propan-1-one, caffeic acid, (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid, (7'S,8R,8'R)-lyoniresinol, (+)-lyoresinol 3a-O-a-L-rhamnopyranoside, garcimangosone, phlorocetophenone 2'-glucopyranoside, (+)-taxifolin 3a-O-a-L-rhamnopyranoside, (+)-aromadendrin, (+)-taxifolin, resveratrol, piceatannol, 3,4,5-trihydroxyphenol. Tachiaside, gallic acid, macrocapals A und G, and oleuropeic acid were evaluated for their cytotoxicities against five human cancer cell lines. Resveratrol, piceatannol, gallic acid, and macrocapal G exhibited moderate inhibitory effects on human myeloid heukemia HL-60 cell, with IC50 values of 22.05, 22.05, 7.75, and 31.93 mu M, respectively; and only macrocapal G showed inhibitory effect on hepatocellular carcinoma SMMC-7721 cell, with an IC50 value of 26.75 mu M.
关键词Eucalyptus Maideni Cytotoxic Activity Phenolic Compounds Eucalmaidin f
资助信息NSFC[2008ZX09401-004, 2011CB915503]
学科领域Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
DOI10.1002/cbdv.201100021
收录类别SCI
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Chemistry
WOS类目Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS记录号WOS:000299154400012
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/10431
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W Chin, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Weihe Biotech Res & Dev Ctr, Yuxi 653101, Peoples R China
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GB/T 7714
Tian, Li-Wen,Xu, Min,Li, Yan,et al. Phenolic Compounds from the Branches of Eucalyptus maideni[J]. CHEMISTRY & BIODIVERSITY,2012,9(1):123-130.
APA Tian, Li-Wen.,Xu, Min.,Li, Yan.,Li, Xing-Yao.,Wang, Dong.,...&Zhang, Ying-Jun.(2012).Phenolic Compounds from the Branches of Eucalyptus maideni.CHEMISTRY & BIODIVERSITY,9(1),123-130.
MLA Tian, Li-Wen,et al."Phenolic Compounds from the Branches of Eucalyptus maideni".CHEMISTRY & BIODIVERSITY 9.1(2012):123-130.
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