Limonoids from the leaves of Toona ciliata var. yunnanensis
Liu, Jie-Qing; Wang, Cui-Fang; Li, Yan; Chen, Jian-Chao; Zhou, Lin; Qiu, Ming-Hua
2012-04-01
发表期刊PHYTOCHEMISTRY
ISSN0031-9422
卷号76页码:141-149
摘要Twelve limonoids, toonayunnanins A-L (1-12) and eleven known compounds (13-23) were isolated from the leaves of Toona ciliata var. yunnanensis, and their structures were elucidated by means of extensive spectroscopic analyses, particularly 1D and 2D NMR techniques. The inhibitory effects of all the isolated compounds were evaluated on human tumor cell lines, such as HL-60, SMMC-7721, A-549, MCF-7 and SW480. Cedrelone (13) and dysobinin (18) showed significant cytotoxicity, and toonayunnanin B (2) and epoxyazadiradione (14), were found to be slightly cytotoxic against the above cell lines. Furthermore, this study provides valuable information for the chemotaxonomy of T. ciliata varieties. (C) 2012 Elsevier Ltd. All rights reserved.
关键词Toona Ciliata Var. Yunnanensis Toona Ciliata Meliaceae Limonoids Nortriterpenoid Toonayunnanins A-l Cytotoxic Activities Baeyer-villiger Type Oxidation
资助信息CAS[KSCX2-YW-G-038, KSCX2-YW-G-027, KSCX2-YW-R-194, KZCX2-XB2-15-03]; Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China[P2008-ZZ05, P2010-ZZ14]
学科领域Biochemistry & Molecular Biology ; Plant Sciences
DOI10.1016/j.phytochem.2012.01.002
收录类别SCI ; IC
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
WOS类目Biochemistry & Molecular Biology ; Plant Sciences
WOS记录号WOS:000302444500017
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/10401
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位Chinese Acad Sci, State Key Lab Photochem & Plant Resources W China, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China
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Liu, Jie-Qing,Wang, Cui-Fang,Li, Yan,et al. Limonoids from the leaves of Toona ciliata var. yunnanensis[J]. PHYTOCHEMISTRY,2012,76:141-149.
APA Liu, Jie-Qing,Wang, Cui-Fang,Li, Yan,Chen, Jian-Chao,Zhou, Lin,&Qiu, Ming-Hua.(2012).Limonoids from the leaves of Toona ciliata var. yunnanensis.PHYTOCHEMISTRY,76,141-149.
MLA Liu, Jie-Qing,et al."Limonoids from the leaves of Toona ciliata var. yunnanensis".PHYTOCHEMISTRY 76(2012):141-149.
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