|Limonoids from the leaves of Toona ciliata var. yunnanensis|
|Liu, Jie-Qing; Wang, Cui-Fang; Li, Yan; Chen, Jian-Chao; Zhou, Lin; Qiu, Ming-Hua
|摘要||Twelve limonoids, toonayunnanins A-L (1-12) and eleven known compounds (13-23) were isolated from the leaves of Toona ciliata var. yunnanensis, and their structures were elucidated by means of extensive spectroscopic analyses, particularly 1D and 2D NMR techniques. The inhibitory effects of all the isolated compounds were evaluated on human tumor cell lines, such as HL-60, SMMC-7721, A-549, MCF-7 and SW480. Cedrelone (13) and dysobinin (18) showed significant cytotoxicity, and toonayunnanin B (2) and epoxyazadiradione (14), were found to be slightly cytotoxic against the above cell lines. Furthermore, this study provides valuable information for the chemotaxonomy of T. ciliata varieties. (C) 2012 Elsevier Ltd. All rights reserved.|
|关键词||Toona Ciliata Var. Yunnanensis
Baeyer-villiger Type Oxidation
|资助信息||CAS[KSCX2-YW-G-038, KSCX2-YW-G-027, KSCX2-YW-R-194, KZCX2-XB2-15-03]; Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China[P2008-ZZ05, P2010-ZZ14]|
|作者单位||Chinese Acad Sci, State Key Lab Photochem & Plant Resources W China, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China|
Liu, Jie-Qing,Wang, Cui-Fang,Li, Yan,et al. Limonoids from the leaves of Toona ciliata var. yunnanensis[J]. PHYTOCHEMISTRY,2012,76:141-149.
Liu, Jie-Qing,Wang, Cui-Fang,Li, Yan,Chen, Jian-Chao,Zhou, Lin,&Qiu, Ming-Hua.(2012).Limonoids from the leaves of Toona ciliata var. yunnanensis.PHYTOCHEMISTRY,76,141-149.
Liu, Jie-Qing,et al."Limonoids from the leaves of Toona ciliata var. yunnanensis".PHYTOCHEMISTRY 76(2012):141-149.